Clinical trials
Acute Ischemic Stroke From Large Vessel Occlusion clinical trials
Below are recruiting acute ischemic stroke from large vessel occlusion clinical trials, each written for real people, not researchers. We’re tracking 99 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07231380Recruiting
Comparing two ways to remove clots in stroke
This study tests two methods of removing a large blood clot from a brain artery during stroke. The goal is to see which method helps restore blood flow faster and more safely.
Nashville, TennesseeAges 18 years+ - NCT06121336Recruiting
Tracking a blood marker to measure stroke recovery
This study is looking at a protein in the blood called brain-derived tau, which may increase after a stroke. By measuring it over time, doctors hope to learn more about how the brain is healing and possibly predict recovery.
Munich, BavariaAges 18 years+ - NCT05065216RecruitingPhase 2/Phase 3
Study drug for acute ischemic stroke started within 24 hours
This trial tests whether an investigational study drug can improve outcomes after an acute ischemic stroke (a stroke caused by blocked blood flow). You may be eligible if you are able to start treatment quickly after symptom onset and have a moderate stroke severity on a standard stroke exam.
Fairhope, AlabamaAges 18–90 - NCT07253181RecruitingPhase 3
Stroke clot-busting drug before transfer for artery clearing
This trial tests whether giving a clot-busting drug (tenecteplase) before transferring you to a hospital that can do a procedure to remove the clot improves outcomes for people who had a stroke up to 24 hours earlier. You may qualify if you have a blockage in a large artery in the front of your brain and can still get the procedure.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06904911RecruitingPhase 2
Study of tenecteplase into the artery after clot removal for stroke
This study tests a clot-dissolving drug called tenecteplase given directly into the artery after a mechanical thrombectomy (clot removal). The goal is to see if it helps improve blood flow to the small vessels in the brain after the main clot is removed.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07727395RecruitingPhase 3
Clot-busting drug after successful clot removal for stroke
This trial tests whether giving a clot-busting drug (alteplase) directly into the brain artery after a successful clot removal improves recovery in people with severe stroke. It is for patients who have had a thrombectomy and still have a large blocked artery in the front of the brain.
An GiangAges 18 years+ - NCT06370182Recruiting
New catheter for clot removal in disabling stroke
This trial tests a new catheter device (ANA Funnel) for removing large blood clots from the brain in people having a disabling stroke. The goal is to see if it safely removes clots better than standard treatment.
Jacksonville, FloridaAges 22–85 - NCT07090941Recruiting
Clot removal for severe basilar artery stroke
This trial tests a procedure to remove a blood clot from the main artery at the back of the brain (basilar artery) in people who have a large stroke. The goal is to see if this treatment can improve recovery even when the stroke damage is bigger than usual.
Haikou, HainanAges 18 years+ - NCT06464731Recruiting
Clot removal for mild stroke due to large artery blockage
This trial tests whether removing a blood clot from a large brain artery (using a catheter through the groin) can help people with mild stroke symptoms. It is for patients whose stroke started within the last 24 hours and who have a blockage in the front part of the brain's blood supply.
Zhangzhou, FujianAges 18–80 - NCT07747701Recruiting
Monitoring brain blood flow after stroke treatment to predict recovery
This study looks at whether monitoring brain blood flow after a blocked artery is opened can help predict if the treatment will be successful. It may help doctors identify who might need additional help after stroke treatment.
BeijingAges 18 years+ - NCT07740018Recruiting
Stroke treatment study for blocked brain arteries
This study looks at how well a procedure to remove blood clots from blocked brain arteries works for people who have had a stroke. It aims to see what factors help people recover better, which could help guide treatment decisions.
SohagAges 18–80 - NCT07085390Recruiting
Comparing two catheters for stroke clot removal
This study compares two types of catheters (thin tubes) used during a stroke procedure to remove a blood clot. The goal is to see which one works better for clearing blockages in large blood vessels in the brain.
Tampa, FloridaAges 18 years+ - NCT07405762Recruiting
Stroke recovery after blood clot removal: brain blood flow study
This trial looks at how blood flow and brain activity change in the first days after a stroke caused by a large blockage in the front part of the brain. It tests if certain patterns can help predict recovery after a procedure to remove the clot.
Xi'an, Shan'xiAges 18–85 - NCT07299981Recruiting
Brain water changes after clot-busting drug for stroke
This study looks at how much water builds up in brain tissue after a stroke is treated with a clot-busting drug. It may help doctors understand who will recover better.
ViennaAges 18 years+ - NCT03601702Recruiting
EmboTrap device for large stroke blockages
This trial studies whether a specific clot-removal device (EmboTrap II) works well for acute stroke caused by a large artery blockage. It may help restore blood flow faster in people who have certain scan patterns and can be treated within 12 hours.
MilanAges 18 years+ - NCT03737786Recruiting
Sedation with collateral support for stroke clot removal
This trial tests a specific sedation approach, along with support during the procedure, for people having emergency clot removal (mechanical thrombectomy) for a certain type of acute ischemic stroke. It may help make the procedure safer and more effective by improving how patients are managed during endovascular treatment.
Los Angeles, CaliforniaAges 18–110 - NCT05051397RecruitingPhase 2
Breathing gas study during clot removal for stroke
This Phase 2 trial tests whether changing breathing gas (CO₂ level) during a mechanical procedure to remove a brain blood clot can improve outcomes for acute ischemic stroke. It may help by protecting the brain during the clot-removal procedure under general anesthesia.
Clermont-FerrandAges 18 years+ - NCT05199662RecruitingPhase 3
IV clot-busting medicine for stroke when standard options don’t fit
This trial tests whether giving IV TNK (tenecteplase) plus standard stroke care can improve outcomes in some people who have a new stroke but cannot get alteplase (another clot-busting drug) and do not have a large blocked artery that can be treated with a procedure. It’s meant for strokes with “mismatch” findings on scans that suggest salvageable brain tissue.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT05281055Recruiting
Registry of clot-removal treatment for sudden large-vessel strokes
This study keeps a record of people treated with a clot-removal procedure (endovascular thrombectomy) for a sudden stroke caused by a blocked large blood vessel in the brain. It focuses on outcomes for patients who can be treated within 24 hours and were independent before the stroke.
TaipeiAges 20 years+ - NCT05363397RecruitingPhase 2
Adjunctive TBO-309 added to stroke clot removal treatment safety
This Phase 2 trial studies whether adding TBO-309 to standard emergency treatment for acute ischemic stroke is safe and tolerable. It may help researchers see if the added drug can be given without causing excessive side effects alongside clot-busting and/or clot-removal procedures.
Camperdown, New South WalesAges 18 years+ - NCT05578300Recruiting
Translating thrombectomy care into real-world practice in Asia-Pacific
This study aims to help endovascular thrombectomy for certain severe strokes work well in everyday hospital care across Asia-Pacific. You may be considered if you’re an adult with a specific type of stroke blocked in a major brain blood vessel.
Linyi, ShandongAges 18 years+ - NCT05659160Recruiting
Triage approach for certain strokes from blocked large brain arteries
This trial studies a way to sort and treat people with a specific type of acute ischemic stroke (caused by a blockage in a large brain artery). It may help doctors choose the best next steps—either a procedure or medication—faster and more appropriately.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT05779215Recruiting
Registry for acute stroke with blocked brain arteries
This study records information about people who have a new acute ischemic stroke caused by a blockage in a larger or medium-sized brain artery. It may help doctors better understand outcomes and care for this stroke type, using data from many patients.
Beijing, Beijing MunicipalityAges Any age - NCT05832762Recruiting
Clot-buster procedure for blocked neck artery stroke
This trial studies whether an emergency clot-removal procedure through the blood vessels (endovascular treatment) helps people who have a stroke caused by a blocked internal carotid artery in the neck. It compares outcomes in patients treated urgently when imaging shows the blockage is likely the main cause.
Montpellier, FanceAges 18 years+
Hear when a new Acute Ischemic Stroke From Large Vessel Occlusion trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for acute ischemic stroke from large vessel occlusion?
- Yes. Clin2 currently lists 99 recruiting acute ischemic stroke from large vessel occlusion studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute ischemic stroke from large vessel occlusion trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute ischemic stroke from large vessel occlusion trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.