Early medication combo to reduce swelling after stroke
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests a combination of medicines given early after a large ischemic stroke to reduce brain swelling. It may help people who have had a stroke in the middle cerebral artery within the last 3 days and have a large area of brain damage.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have had a stroke caused by a blocked artery in the middle of the brain within the last 3 days.
- The stroke area is large (80–300 mL) or has a low ASPECTS score (1–5) on a brain scan.
- You are not scheduled for a surgery to remove part of your skull to reduce brain pressure.
- You do not have severe low blood pressure (less than 90 systolic) or signs of brain herniation.
- You are not allergic to certain blood pressure or heart rate medications (like terazosin, urapidil, esmolol, or propranolol).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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