Study of a new antibody combination for advanced lung cancer after targeted therapy
Treatments studied
Part of Cancer, Lungs & breathing clinical trials.
This trial tests a new drug (JS207) that targets both PD-1 and VEGF pathways, given alone or with other treatments, for people with advanced non-small cell lung cancer that has a specific gene change and has stopped responding to targeted therapy (TKI). The goal is to see if this combination can help shrink tumors or slow cancer growth.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 18 and 75 years old
- Have advanced lung cancer (non-squamous type) with a specific gene change (like EGFR, ALK, ROS1, or others)
- Your lung cancer must have gotten worse after trying a targeted therapy (TKI), and there are no other standard targeted treatments available
- Have at least one tumor that can be measured on scans
- Be in good enough health to be up and about (ECOG score 0 or 1)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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