Humira injections for artificial cornea surgery
Treatments studied
Part of Eyes & vision, Immune system & allergy, Mouth & dental, Skin clinical trials.
This trial tests a drug called Humira (adalimumab) given as an injection under the eye during artificial cornea surgery. The drug may help reduce inflammation and improve the chance of success for this complex procedure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You need to be eligible for an artificial cornea (keratoprosthesis) surgery, which is usually for people with severe corneal scarring or failed transplants.
- Your vision in the eye being treated must be very poor (worse than 20/200), and the other eye must also have limited vision (worse than 20/40).
- You must be able to wear a contact lens after surgery.
- You must not have active infections like tuberculosis, hepatitis B or C, or other uncontrolled infections.
- You must not have conditions like multiple sclerosis, heart failure, or uncontrolled cancer.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares two types of cornea transplant surgery (PKP and DSAEK) to see which one helps people with severe corneal swelling see better after two years. It may be an option if you have advanced bullous keratopathy and need a first-time cornea transplant.
This study tests whether treating donor corneal tissue with a special light and vitamin drops (called cross-linking) before a transplant helps improve outcomes for people with keratoconus. If you need a corneal transplant, this could strengthen the donor tissue and potentially reduce the need for future procedures.
This study tests an artificial cornea (a small plastic implant) to see if it can safely improve vision in people who are blind from corneal damage and cannot have a regular cornea transplant. It aims to help those with no other good treatment options.
This trial tests infliximab—given as eye drops—after a first corneal transplant to see if it can improve healing and eye outcomes. It may help people at risk of inflammation after surgery, but it also requires careful screening for infection and medication safety.
This trial tests a new corneal implant to treat corneal swelling caused by Fuchs' dystrophy or after cataract surgery. It aims to improve vision and reduce the need for a full corneal transplant.
This study tests a procedure called Xenia corneal lenticule in people with severe keratoconus or severe post-LASIK corneal thinning who want to avoid a corneal transplant. It aims to improve vision while checking safety and how well the new procedure works over time.
Hear when a new Stevens-Johnson Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.