Clin2
NCT06928649Worth exploringRecruiting

Studying cell damage in critically ill ICU patients

SepsisTrauma Related InjuriesSubarachnoid Haemorrhage (SAH)

Treatments studied

Part of Brain & nervous system, Heart & circulation, Infections clinical trials.

This trial looks at specific cell damage processes (called ferroptosis and pyroptosis) in very sick ICU patients. The goal is to learn more about these processes so doctors can better treat life-threatening organ failure caused by conditions like sepsis, trauma, or severe bleeding.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
600 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are currently in the ICU at the University Hospital of Antwerp.
  • Your illness is serious enough that doctors expect you to stay in the ICU for more than 48 hours.
  • You have an arterial line (a small tube in an artery for blood pressure monitoring and blood draws).
  • You or your family have given permission for you to take part.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07353970Not yet recruiting
Severe infection and sepsis study

This study looks at how certain natural molecules in your blood might affect recovery from severe infections or sepsis. By understanding these molecules, doctors hope to better predict outcomes and personalize treatment for patients in the ICU.

NCT05110937Recruiting
Testing immune cell changes in sepsis and trauma shock

This study looks at abnormal immune cells (from the bone marrow) in people with sepsis or severe trauma with shock. It aims to understand why the body’s immune response gets out of balance, which could help guide future treatments.

Gainesville, Florida
NCT07160426Not yet recruiting· Phase 2
Study of a treatment for severe infections (sepsis)

This trial tests a new treatment to protect and repair the layer of cells lining your blood vessels (glycocalyx) during sepsis. It aims to improve recovery from severe infections.

NCT04103281Recruiting
Blood test study of immune cell markers in ICU sepsis

This trial looks at patterns in certain immune cells (neutrophils) in people with sepsis in the ICU, including those who have a breathing tube. It may help doctors better understand how the immune system changes during sepsis and could guide future care.

Boston, Massachusetts
NCT07332793Not yet recruiting
Immune cell study for severe infections in the ICU

This study looks at how your immune cells respond during a severe infection in the ICU. It aims to better predict how the infection will progress and help tailor treatment.

NCT05591924Recruiting
Bioinformatics study in adults with very early severe ICU illness

This trial studies how early severe illness in the ICU can be understood and tracked using health data (bioinformatics/informatics). It may help improve care decisions for people who arrive to the ICU soon after an emergency department visit.

London, Ontario

Hear when a new Sepsis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.