Melatonin or dexmedetomidine before anesthesia for people with high blood pressure
Treatments studied
Part of Heart & circulation clinical trials.
This study tests two medicines given before surgery to see which one better controls blood pressure and heart rate during the start of anesthesia. It may help people with high blood pressure have a safer and smoother experience when they are put to sleep for surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 40 and 60 years old.
- You have high blood pressure that is controlled with medication.
- You are scheduled for elective surgery that requires general anesthesia (you will be fully asleep).
- You do not have severe heart, liver, or kidney disease.
- You are not taking certain medicines like beta-blockers, antidepressants, or thyroid medications.
- You are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether giving a single dose of dexmedetomidine (a medicine that helps calm the body's stress response) before surgery can reduce the stress on your heart and blood pressure when a breathing tube is placed. It may help you recover more smoothly.
This trial compares two medicines (dexmedetomidine and labetalol) to see which one better controls stress on the airway during brain surgery in people with high blood pressure. The goal is to find a safer way to manage your heart rate and blood pressure while you are under anesthesia.
This study tests if dexmedetomidine can help prevent dangerous blood pressure spikes during breathing tube placement for surgery in patients with high blood pressure. It is for older adults (over 60) who have been managing their hypertension for at least 6 months.
This trial tests if adding a second medicine, ketamine, to dexmedetomidine helps control blood pressure better during ear or nose surgery. It may lead to safer and smoother anesthesia for patients needing controlled low blood pressure.
This trial tests whether dexmedetomidine or lignocaine better prevents dangerous heart-rate and blood-pressure changes when a breathing tube is placed during heart surgery. If you're having cardiac surgery and are at high risk for heart complications, this study may help protect your heart during the procedure.
This study compares two medications, dexmedetomidine and lignocaine, to see which one better keeps your heart rate and blood pressure stable when the breathing tube is removed after surgery. It aims to find a safe and effective option, especially in settings with limited resources.
Hear when a new Laryngoscopy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.