Colchicine before and after knee replacement surgery
Treatments studied
Part of Bones, joints & muscles, Pain clinical trials.
This trial tests if taking colchicine around the time of knee replacement surgery can improve recovery. Colchicine is a medicine that reduces inflammation, which might help with pain and healing after surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older and scheduled for knee replacement because of arthritis.
- Your liver and kidneys work well enough (no severe liver disease or kidney problems).
- You have not had a bad reaction to colchicine before.
- You do not take strong pain medicines (opioids) regularly (more than twice in the last 6 months).
- You are not pregnant or planning to become pregnant during the first few days after surgery.
- You are not taking certain medicines that could interact with colchicine (like some antifungals, antibiotics, heart medicines, or statins).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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