Heart cell patch for severe heart failure
Part of Heart & circulation clinical trials.
This trial tests a patch made from lab-grown heart muscle cells that is placed on the heart during bypass surgery. It aims to see if the patch can improve heart function in people with severe heart failure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You have advanced (Stage D) heart failure that doesn't improve with standard medicines.
- You are being considered for coronary artery bypass surgery (CABG).
- Your heart's pumping strength (ejection fraction) is 40% or less.
- You do NOT have a permanent pacemaker, ICD, or CRT device.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether a special collagen patch containing stem cells can help people recover heart function after a heart attack. You would get the patch placed on your heart during bypass surgery.
This trial tests whether injecting special cells (HiCM-188) during bypass surgery can help improve heart function in people with advanced heart failure. The cells may help repair damaged heart tissue and improve your heart's ability to pump blood.
This trial tests whether heart muscle cells made from stem cells, injected into the heart, can improve heart function in people with heart failure and a weak heart pump. It may be an option for those who are not getting enough help from other treatments.
This trial tests a new treatment using your own bone marrow cells to help your heart pump better. It's for people with heart failure after a heart attack whose heart function is moderately reduced.
This early-phase study tests a lab-made heart tissue (“engineered myocardium”) placed surgically to help the heart work better in people with advanced heart failure. It mainly checks safety first, and also looks for signs the patch can improve heart function in selected patients.
This trial tests a treatment made from stem cells that are turned into heart muscle cells and injected directly into the heart. It is for people with advanced heart failure who are already on the best available medicines and who are scheduled to have bypass surgery.
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