Preventing blood clots after knee replacement with H001
Treatments studied
Part of Blood & lymphatic clinical trials.
This trial tests whether an experimental capsule (H001) can prevent dangerous blood clots after knee replacement surgery. It is for people who are scheduled for a first-time total knee replacement and are willing to take the study drug instead of standard blood thinners.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 74 years old and scheduled for a knee replacement surgery on one knee.
- You must be willing to use effective birth control during the study (if you or your partner could become pregnant).
- You cannot have a history of bleeding problems, blood clots, or recent serious heart issues.
- You cannot currently be taking strong blood thinners or certain medications like high-dose aspirin or NSAIDs.
- You cannot have had major surgery or a serious injury in the past 3 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new injection called SRSD107 to see if it prevents blood clots after knee replacement surgery, compared to a standard blood thinner (enoxaparin). It might be an option if you are having a planned knee replacement and are otherwise healthy.
This trial compares a new blood thinner called REGN7508 to two standard blood thinners (apixaban and enoxaparin) to prevent blood clots after total knee replacement surgery. The goal is to see which is safer and more effective.
This trial compares a personalized approach to preventing blood clots after hip or knee replacement surgery with the standard one-size-fits-all method. The goal is to see if tailoring prevention to each patient works better and is safer.
This trial tests a new medicine called REGN7508 against aspirin to prevent blood clots after total knee replacement surgery. It may help if you are having a planned knee replacement and are in good health.
This trial tests an experimental drug called BT-114143 to see if it reduces bleeding during and after total knee replacement surgery. It may be a good option for people with osteoarthritis who are having their first knee replacement.
This study tests a shorter course of blood thinner medication (rivaroxaban) after hip replacement surgery, following an enhanced recovery plan. It aims to see if a shorter treatment can safely prevent blood clots and help you recover faster.
Hear when a new Circulatory Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.