Clin2
NCT06968624Possibly a fitNot yet recruiting

Ketamine for nerve pain and depression after shingles

Depression DisordersHerpetic Neuralgia

Part of Infections, Mental health, Pain clinical trials.

This trial tests whether the medicine ketamine can help relieve nerve pain from shingles and also improve mood in people who have both pain and depression. If you have shingles-related nerve pain and feel depressed, this study might offer a new treatment option.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
50 people
Ages
18 years to 65 years
Study type
Interventional

Who can take part

  • You have nerve pain that started after a shingles infection and has lasted more than a month.
  • You have depression, based on a doctor's diagnosis and a score of 15 or higher on a standard depression test.
  • You are between 18 and 65 years old.
  • Your body mass index (BMI) is under 30.
  • You do not have severe heart, lung, liver, or kidney disease.
  • You are not allergic to ketamine and do not have other mental health conditions like anxiety.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06896994Recruiting
Study of esketamine plus pregabalin and duloxetine for shingles nerve pain

This trial tests whether adding esketamine to two standard pain medicines (pregabalin and duloxetine) can better treat nerve pain from shingles that persists for months. It's for people whose pain hasn't improved enough with pregabalin alone.

Beijing, Beijing Municipality
NCT06914206Not yet recruiting
Esketamine added to nerve block for recent shingles pain

This study tests whether adding a medicine called esketamine to a standard nerve block procedure can improve pain relief for people with shingles-related nerve pain. If you have had shingles pain for less than 3 months, this might help reduce pain and prevent long-term discomfort.

Beijing, Beijing Municipality
NCT06914180Not yet recruiting
Esketamine plus nerve procedure for facial shingles pain

This trial tests whether adding a medication called esketamine to a standard nerve procedure (pulse radiofrequency) can better reduce facial pain from shingles. Esketamine may help block pain signals more effectively.

Beijing, Beijing Municipality
NCT06914193Not yet recruiting
Esketamine plus nerve block for shingles-related pain

This study tests a combination of two treatments for long-term nerve pain after shingles: a medication called esketamine and a nerve block (pulsed radiofrequency) applied to the affected spinal nerves. The goal is to see if this combination relieves the burning or shooting pain better than the nerve block alone.

Beijing, Beijing Municipality
NCT06890897Recruiting
Esketamine with pulsed radiofrequency for shingles-related face pain

This trial tests whether adding esketamine (a medicine related to ketamine) to a standard nerve treatment (pulsed radiofrequency) can better relieve face pain caused by shingles. It may help if you have ongoing, moderate-to-severe pain in your face or scalp.

Beijing
NCT06978192Recruiting· Phase 2
Study for treating shingles pain with a special nerve block

This trial tests a combination of two treatments to reduce shingles pain that hasn't responded to standard medicines. It involves a nerve block to see if it can help people who have ongoing pain after shingles.

Zunyi, Guizhou

Hear when a new Depression Disorders trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.