Rilzabrutinib for sickle-cell disease pain episodes
Treatments studied
Part of Blood & lymphatic, Genetic & congenital clinical trials.
This study tests an oral medicine called rilzabrutinib to see if it can reduce painful episodes in people with sickle-cell disease. It may be an option if you have regular pain crises and are looking for a new treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have sickle-cell disease.
- You've had between 2 and 10 painful episodes (VOCs) in the last year.
- You are either not taking hydroxyurea or L-glutamine, or you have been taking them stably for at least 6 months.
- You must be able to do most daily activities (ECOG score 0–2).
- You must not have had a stroke or abnormal brain blood flow.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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