Blood thinner dosing for children with Kawasaki aneurysm
Treatments studied
Part of Blood & lymphatic, Heart & circulation, Skin clinical trials.
This study tests the best dose of a blood thinner called rivaroxaban for children with a giant coronary artery aneurysm after Kawasaki disease. The goal is to prevent dangerous blood clots.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child has a giant coronary artery aneurysm (a very wide blood vessel in the heart) after Kawasaki disease.
- Your child is at least 1 month old and weighs at least 5.7 pounds (2600 grams).
- Your child can take medicine by mouth or through a feeding tube.
- Your child does not have active bleeding or a high bleeding risk, severe kidney problems, or other conditions that would make blood thinners unsafe.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial studies whether rivaroxaban (a blood thinner) can help prevent dangerous clots in children age 2 and older who have “giant” coronary artery aneurysms after Kawasaki disease. Doctors will see if it’s safe and tolerable for children who are also on standard anti-clot/anti-platelet medications for the next 3 months.
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