CAR-T cell therapy for blood cancers that have returned
Treatments studied
Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.
This trial tests a new type of immunotherapy called CAR-T cells, which are engineered to attack cancer cells that have certain markers (CD19 or BCMA). It is for people with blood cancers like multiple myeloma or certain lymphomas that have not responded to multiple prior treatments. The goal is to see if this treatment can help when other options have failed.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a type of blood cancer that is positive for CD19 or BCMA markers on the cancer cells.
- For multiple myeloma, plasma cell leukemia, or lymphoma with plasma cells, you must have tried at least 3 prior treatments and they stopped working or the cancer came back.
- If you have AL amyloidosis (a protein buildup disease), you must have had at least 2 prior treatments that failed.
- You must be between 18 and 80 years old.
- You must be in fairly good health, able to do daily activities, and have adequate heart, lung, liver, and blood function.
- If you can become pregnant, you must use effective birth control during the study and for 1 year after the CAR-T infusion.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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