Decitabine plus standard therapy for HPV-negative head and neck cancer
Treatments studied
Part of Cancer, Ear, nose & throat clinical trials.
This trial tests whether adding the drug decitabine to standard treatment (surgery and possibly radiation) can help people with a type of head and neck cancer not caused by HPV. You would receive decitabine before surgery, and then continue with standard care after.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older.
- You have a type of head and neck cancer (squamous cell) that is not caused by HPV and can be removed with surgery.
- You have not had previous chemotherapy or radiation to the same area in the last 5 years.
- You are in good enough health to have surgery and can go about your daily activities without much help (ECOG 0 or 1).
- Your blood counts and organ function (kidney, liver) are within a certain range.
- If you could become pregnant, you agree to use birth control and have a negative pregnancy test.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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