Drug study to slow hardening of aortic valve disease
Part of Heart & circulation clinical trials.
This Phase 2 trial tests pelacarsen (TQJ230), a medication that lowers a blood fat called lipoprotein(a), to see if it slows progression of calcific aortic valve stenosis. It may help people whose valve narrowing is starting to become more severe, especially when their lipoprotein(a) level is high.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 50 to under 80
- Your lipoprotein(a) blood level is high (at least 175 nmol/L)
- You have mild or moderate calcific aortic valve stenosis (not severe)
- Your blood pressure and other heart risk factors must be well controlled
- You are not pregnant or nursing
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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