Finding the best oxygen flow setting after extubation
Part of Lungs & breathing clinical trials.
This trial tests different flow rates for a high-flow nasal cannula (a device that delivers warm, moist oxygen) after a breathing tube is removed. It aims to find the best setting for patients moving from a ventilator to breathing on their own.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been on a breathing machine (ventilator) for more than 24 hours
- You are ready to have your breathing tube taken out and passed a test to see if you can breathe on your own
- Your oxygen level in the blood is below a certain threshold (PaO2/FiO2 less than 350) on the day your tube is removed
- You are 18 years or older
- You do not have a do-not-reintubate order
- You are not pregnant
- You do not have a tracheostomy tube in your throat
- You can use a high-flow nasal cannula
- You are not planning to use preventive non-invasive ventilation (a mask that blows air) after the tube is removed
- You are expected to live more than one month
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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