Immunotherapy and biologic for house dust mite allergic asthma
Treatments studied
Part of Ear, nose & throat, Immune system & allergy, Lungs & breathing clinical trials.
This trial tests whether adding an allergy immunotherapy tablet (which helps your immune system get used to dust mites) to a biologic treatment (tezepelumab, which reduces airway inflammation) can keep severe asthma under control better than the biologic alone. It may help reduce asthma attacks and improve daily symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You have severe asthma that is not well controlled, and you have had at least two asthma attacks in the last year.
- You are allergic to house dust mites, confirmed by a skin test and a blood test.
- You have not taken certain allergy immunotherapy (allergy shots or under-the-tongue tablets) for dust mites in the past 5 years.
- You are not currently using other biologic asthma treatments (like omalizumab or dupilumab), and you have not had one within the last 3 months.
- You are not regularly exposed to other common allergens like animal dander, mold, or cockroaches.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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