Autologous serum eye drops for dry eye and corneal damage
Part of Eyes & vision, Immune system & allergy, Mouth & dental, Skin clinical trials.
This study makes eye drops from your own blood serum (the liquid part of blood) to help heal dry or damaged corneas. The serum is collected in a special closed system, then used as drops to soothe and repair the eye surface.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be at least 18 years old.
- You must have dry eye or a slow-healing wound on the clear front part of your eye (the cornea).
- You must be able to have blood drawn from a vein in your arm or from a PICC line.
- You cannot have an active eye or body infection.
- You cannot have low red blood cell counts (anemia) or certain cancers like blood cancer.
- You cannot have HIV, hepatitis B or C, Chagas disease, or syphilis.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether eye drops made from your own blood serum (with a natural lubricant) can relieve moderate-to-severe dry eye better than a standard salt solution. If you have dry eye from certain immune conditions or nerve damage, this may help find a more effective treatment.
This trial tests whether eye drops made from your own blood can help treat moderate to severe dry eye that hasn't improved with artificial tears.
This study tests a new eye drop treatment made from your own blood serum for severe dry eye that hasn't improved with standard treatments. Researchers will analyze proteins in your tears to understand why this treatment works and who benefits most.
This study compares two types of blood-derived treatments (a growth-factor enriched plasma product versus your own serum) to see which helps corneal cells heal better in people with aniridia. It may be helpful if you need improved cornea healing, but you must meet blood-safety and eye-sample requirements.
This trial tests an eye drop solution for people with chronic dry eye caused by graft-versus-host disease after a stem cell transplant. It aims to see if the drops can reduce eye discomfort and improve the eye surface.
This study tests whether a new eye drop (rhPRG4) can safely reduce dry eye symptoms caused by graft-versus-host disease (GVHD). It compares the active drops to an inactive placebo to see if they provide better relief.
Hear when a new Meibomian Gland Dysfunction (Disorder) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.