Clin2
NCT07036250Possibly a fitRecruiting

Study of U32 for acute myeloid leukemia

Acute Myeloid Leukaemia

Part of Blood & lymphatic, Cancer clinical trials.

This trial tests a new treatment called U32 for people with acute myeloid leukemia (AML) that has come back or not responded to prior therapy. It aims to see if targeting certain proteins on leukemia cells can help control the disease.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
20 people
Ages
2 years to 65 years
Study type
Interventional

Who can take part

  • You are between 2 and 65 years old.
  • You have acute myeloid leukemia (AML) that has returned or not responded to at least two prior treatments or a stem cell transplant.
  • Your leukemia cells have a protein called CD38 or CLL-1 on them.
  • You are in fairly good health, able to do daily activities with some help (ECOG score 0-3).
  • Your blood counts and organ function are adequate, and you can undergo apheresis (a process to collect cells).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06762132Recruiting· Early Phase 1
CD33 car-t cell therapy for returning or hard-to-treat aml

This trial tests a personalized cell therapy called CD33 CAR-T for people whose acute myeloid leukemia has come back or isn't responding to standard treatments. The goal is to see if it's safe and can help eliminate leukemia cells that carry the CD33 protein.

Hangzhou, Zhejiang
NCT06326021Recruiting· Phase 1
CD33 CAR T for relapsed or refractory AML

This trial tests a new type of immune therapy called CAR T cells that target the CD33 protein on leukemia cells. It is for people with AML that has returned or not gone away after standard treatments, and who have a stem cell donor available for a transplant afterward.

Shanghai, Shanghai Municipality
NCT07198867Recruiting· Phase 1
A-CAR028 for relapsed or refractory AML

This trial tests a new cell therapy called A-CAR028 for people with acute myeloid leukemia (AML) that has come back or not responded to treatment. The therapy uses your own immune cells to fight the cancer.

Hangzhou, Zhejiang
NCT06760260Recruiting· Early Phase 1
FLT3-targeted CAR-T cell therapy for relapsed AML

This trial tests a new treatment made from your own immune cells (CAR-T cells) that are designed to find and kill leukemia cells that have the FLT3 protein. It is for people with acute myeloid leukemia (AML) that has not responded to standard therapy or has returned after treatment.

Suzhou, Jiangsu
NCT07668557Recruiting· Phase 1
CLL1-CD33 CAR-T cells for relapsed or refractory acute myeloid leukemia

This trial tests a new type of immune cell therapy (CAR-T) designed to find and kill leukemia cells that carry two specific markers (CLL-1 and CD33). It is for adults with acute myeloid leukemia that has come back or is not responding to standard treatments.

Nanchang, Jiangxi
NCT07538713Not yet recruiting· Phase 1
CD33 CAR-T Cell Therapy for Hard-to-Treat Blood Cancer

This trial tests a new type of immune cell therapy (called CAR-T) designed to target and fight acute myeloid leukemia (AML) that has come back or didn't respond to standard treatments. The therapy uses your own immune cells, modified in the lab to recognize and kill leukemia cells.

Hear when a new Acute Myeloid Leukaemia trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.