Clin2
NCT07039656Possibly a fitRecruiting

Toripalimab plus chemo after NSCLC surgery

Stage IB-IIIB NSCLCStage IIB-III NSCLC

Treatments studied

Part of Cancer, Lungs & breathing clinical trials.

This trial tests adding the immunotherapy drug toripalimab to chemotherapy after surgery for non-small cell lung cancer (NSCLC). It is for patients who either had no treatment before surgery or had chemo-immunotherapy before surgery and still have signs of cancer in their lymph nodes. The goal is to see if this combination helps prevent cancer from coming back.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
211 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old.
  • You have a type of lung cancer called non-small cell lung cancer (NSCLC) that was removed completely by surgery within the last 60 days.
  • You either did not receive any anti-cancer treatment before surgery, or you had chemo-immunotherapy before surgery and still have cancer in your lymph nodes.
  • Your cancer does not have changes (mutations) in the EGFR or ALK genes.
  • You are in generally good health (ECOG performance status 0 or 1) and your organs are working well.
  • You are willing to use effective birth control during the study and for 6 months after the last dose.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06426511Recruiting· Phase 2
Testing toripalimab after lung cancer surgery using ctDNA

This study tests whether a drug called toripalimab, given after lung cancer surgery, can help keep the cancer from coming back in people with early-stage non-small cell lung cancer. It uses a blood test (ctDNA) to look for leftover cancer cells and decide who might benefit most.

Guangzhou, Guangdong
NCT04992559Recruiting· Phase 2
Toripalimab after surgery and chemoradiation for head and neck cancer

This trial studies toripalimab to lower the risk of the cancer coming back after surgery and additional chemo-radiation. It may help the immune system “finish the job” after your main treatment, especially if you have higher-risk features.

Guangzhou, Guangdong
NCT06221670Recruiting· Phase 2
Toripalimab after surgery for high-risk early lung cancer

This trial tests whether giving a drug called Toripalimab after surgery can help prevent early-stage non-squamous non-small cell lung cancer from coming back. It is for people whose tumors have high-risk features and PD-L1 levels of at least 1%.

Tianjin, Tianjin Municipality
NCT05891080Not yet recruiting· Phase 2
Immunotherapy plus chemo before surgery for stage III lung cancer

This trial tests a new combination of drugs given before surgery for stage III lung cancer. It aims to shrink the tumor to make surgery more effective and possibly improve your chances of a cure.

NCT07097948Not yet recruiting· Phase 2
Immunotherapy plus chemotherapy after surgery for small cell lung cancer

This trial tests whether giving an immunotherapy drug called toripalimab together with chemotherapy after lung cancer surgery can help prevent small cell lung cancer from coming back. It is for people who had surgery to remove lung cancer and were found to have small cell lung cancer in the removed tissue.

Shanghai, China
NCT04772287Not yet recruiting· Phase 3
Immunotherapy plus chemotherapy after lung cancer surgery

This trial tests whether adding the immunotherapy drug toripalimab to standard chemotherapy after lung cancer surgery can help stop the cancer from coming back. It is for people with non-small cell lung cancer that has not spread to the brain and does not have certain genetic changes (EGFR/ALK mutations).

Hear when a new Stage IIB-III NSCLC trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.