Extended-release sodium oxybate for voice spasms and tremor
Part of Brain & nervous system, Ear, nose & throat, Lungs & breathing clinical trials.
This trial tests whether an extended-release form of sodium oxybate (Lumryz) can safely and effectively treat spasmodic dysphonia and voice tremor. It is for people who have already responded well to the immediate-release version (Xyrem) in earlier studies.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 21 and 80 years old.
- You have a confirmed diagnosis of alcohol-responsive laryngeal dystonia (a voice condition that gets better with alcohol).
- You have had a positive response to the immediate-release form of sodium oxybate (Xyrem) in a prior study.
- You are willing to follow the study medication schedule and lifestyle rules.
- You do not have certain health conditions like severe liver or kidney problems, heart failure, or a history of suicidal thoughts or alcohol use disorder.
- You are not pregnant or breastfeeding, and if you had botulinum toxin injections, it has been at least 3 months and you are fully symptomatic again.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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