Sacituzumab plus pembrolizumab for triple-negative breast cancer
Part of Cancer clinical trials.
This trial tests a combination of two drugs, sacituzumab tirumotecan and pembrolizumab, given before surgery for triple-negative breast cancer (a type of breast cancer that lacks three common markers). The study aims to see if this treatment can shrink tumors and improve outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have stage II or III triple-negative breast cancer (tumor size and spread to lymph nodes within certain limits).
- You have not received any prior treatment for this breast cancer diagnosis.
- You are in good overall health (ECOG score 0-1), meaning you can carry out daily activities without much difficulty.
- You have a tumor sample available for testing, and at least one measurable tumor on scans.
- Your blood counts and organ function (kidneys, liver, heart) meet specific lab criteria.
- You agree to use effective contraception if you could become pregnant or father a child.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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