Cefazolin Dose Before Shunt Surgery: Checking Brain Fluid Levels

This trial tests if the antibiotic ceftriaxone can prevent early pneumonia in patients on breathing machines after a serious brain injury.

This study looks at how a common antibiotic (cefazolin) spreads in the body of young children who have had heart surgery for certain congenital heart defects. It may help doctors learn the best way to give antibiotics to prevent infections after surgery.

This study compares a new way of delivering antibiotics directly into the bone during hip replacement surgery versus the standard IV method. The goal is to see if this approach prevents infection just as well while potentially improving outcomes.

This study tests whether a special antibiotic powder (vancomycin) applied during brain fluid shunt surgery can prevent infections in children. Brain shunts drain excess fluid from around the brain, and infections are a common complication—this trial aims to reduce that risk and see if the treatment is cost-effective.

This study compares two ways of giving the antibiotic cefazolin during major orthopedic surgery: as a continuous drip (through an IV line over hours) versus as short shots (boluses) at certain times. The goal is to see which method better prevents infections at the surgical site.

This trial tests whether giving the antibiotic cefazolin as a steady drip (continuous infusion) works better than giving it in quick doses (intermittent bolus) to prevent infections after coronary artery bypass graft (CABG) surgery. It is for Egyptian patients who are admitted to the cardiothoracic ICU.