Clinical trials
Antibiotic Prophylaxis clinical trials
Below are recruiting antibiotic prophylaxis clinical trials, each written for real people, not researchers. We’re tracking 32 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07557901Enrolling by invitation
Antibiotics to prevent infection after prostate biopsy
This study tests whether taking antibiotics before a prostate biopsy (a needle procedure to check for cancer) reduces infections. You would receive either standard care or a specific antibiotic plan, and researchers will track any infections that develop.
Banská BystricaAges Any age - NCT07549542Enrolling by invitationPhase 4
Testing antibiotic delivery method for hip replacement surgery
This study compares a new way of delivering antibiotics directly into the bone during hip replacement surgery versus the standard IV method. The goal is to see if this approach prevents infection just as well while potentially improving outcomes.
Somerset, New JerseyAges 18 years+ - NCT05502380RecruitingPhase 3
Antibiotic prevention study for high-risk bone and spine surgeries
This Phase 3 study tests whether giving a broad set of preventive antibiotics before certain high-risk orthopedic surgeries lowers the chance of serious wound or bone infection. It mainly targets people who have contaminated wounds, tumor-related surgery, or known high-risk germs on the skin.
ZurichAges 18 years+ - NCT06709196RecruitingPhase 4
Targeted antibiotics to prevent infections after bladder removal
This trial tests if using a personalized antibiotic approach before surgery can reduce infections compared to the usual one-size-fits-all antibiotics. It focuses on people having their bladder removed (cystectomy) with a specific type of urinary diversion.
AalborgAges 18 years+ - NCT06810687Recruiting
Methenamine vs. antibiotics to prevent UTIs after sling surgery
This study compares a non-antibiotic medicine (methenamine) to antibiotics for preventing urinary tract infections after a common incontinence surgery (mid-urethral sling). It may help people avoid antibiotics and their side effects.
Morristown, New JerseyAges 18–100 - NCT06778083Recruiting
Antibiotic to prevent STIs and its effect on resistance
This study looks at taking doxycycline to prevent sexually transmitted infections (STIs) in men who have sex with men. It focuses on how this approach might affect the body's resistance to antibiotics.
LondonAges 18 years+ - NCT07053943Enrolling by invitation
Comparing single vs. multiple antibiotic doses for hip and knee replacement
This study compares two ways of giving antibiotics before hip or knee replacement surgery to see which one leads to fewer infections needing another surgery. It may help doctors choose the best antibiotic approach for patients having their first joint replacement.
Amsterdam, North HollandAges Any age - NCT06576154RecruitingPhase 3
Antibiotics to prevent infection after hernia repair in high-risk patients
This trial tests whether giving antibiotics before surgery can lower the chance of infection after groin hernia repair in people who are at higher risk due to age, diabetes, obesity, or other health conditions. If you're over 60 and have one of these risk factors, this study may help you avoid a wound infection.
AleppoAges 18 years+ - NCT07107477RecruitingPhase 3
Tailored therapy for preterm membrane rupture to prolong pregnancy
This trial tests a personalized treatment plan for people whose water breaks too early (before 34 weeks). The goal is to safely extend the pregnancy and improve health outcomes for both the parent and baby, while reducing the use of antibiotics.
BrnoAges 18 years+ - NCT05571722RecruitingPhase 4
Antibiotic prevention for surgical site infections
This trial tests whether using linezolid or vancomycin before surgery can better prevent infections at the surgical wound in people at higher risk. You might be considered because you either can’t take certain standard antibiotics (beta-lactams) and/or may carry MRSA bacteria.
MarseilleAges 18 years+ - NCT05519072RecruitingPhase 4
Antibiotics before bladder Botox injections
This study looks at whether taking antibiotic medicine before bladder Botox reduces infection risk or complications. It’s for adults having bladder Botox treatments and who can safely take antibiotics by mouth.
Morristown, New JerseyAges 18 years+ - NCT05813184Recruiting
Prenatal antibiotics and breast milk effects on newborn immunity
This study looks at how taking antibiotics during late pregnancy affects a baby’s early immune protection, with breastfeeding as an important factor. You may be able to join if you plan to breastfeed and either received antibiotics for at least 7 days after 32 weeks or did not receive such antibiotics during pregnancy.
MilanAges 18–40 - NCT07246967Recruiting
Preventing infection after kidney stone surgery
This trial tests if using a special suction tube during surgery to remove kidney stones can lower the risk of infection. It is for people with small to medium-sized stones in the kidney or upper ureter.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06953271RecruitingPhase 4
Methenamine after Botox for bladder control
This study tests whether taking a medication called methenamine hippurate (a pill for preventing UTIs) after Botox bladder injections can help reduce the risk of urinary tract infections. It may be a good option for women and non-binary people with overactive bladder who are already getting Botox treatment.
Providence, Rhode IslandAges 18 years+ - NCT05319067Recruiting
Gut bacteria study in toddlers on long-term reflux antibiotics
This study compares gut bacteria (microbiome) in toddlers who take an antibiotic to prevent urine infections for vesicoureteral reflux, versus other similar children. It may help researchers understand how long-term antibiotic use and reflux affect gut health and future risk.
MontpellierAges 1–3 - NCT04444440RecruitingPhase 4
Antibiotic prevention after bladder Botox for overactive bladder
This trial studies whether taking an antibiotic around the time of bladder Botox can lower the risk of urinary infections. It’s for women with overactive bladder who tried standard medicines but didn’t get enough relief.
Edmonton, AlbertaAges 18 years+ - NCT07342647Recruiting
Safer antibiotics for people with beta-lactam allergies in joint replacement surgery
This trial tests a better way to choose antibiotics during joint replacement surgery for patients who are allergic to beta-lactams (a common class of antibiotics). The goal is to prevent infections while avoiding allergic reactions.
StrasbourgAges 18 years+ - NCT04140578RecruitingPhase 4
Antibiotic prevention for certain liver disease patients
This trial tests whether taking preventive antibiotics can help people with certain liver conditions avoid infections after an endoscopy-related procedure. It may reduce infection risk, but it also requires that you have no signs of infection and haven’t recently taken antibiotics.
TaipeiAges 20–85 - NCT04791579RecruitingPhase 2
Preventing UTIs after Botox for neurogenic bladder
This study tests whether taking an antibiotic (ciprofloxacin) around the time of bladder Botox can prevent urinary tract infections (UTIs) in people whose bladder problems are caused by nerve conditions. It may help lower the chance of infection after treatment.
Edmonton, AlbertaAges 18–100 - NCT05784311RecruitingPhase 4
Longer vs shorter antibiotic prevention after pancreatoduodenectomy
This trial compares a standard length of preventive antibiotics versus a longer course after Whipple surgery to see if it lowers infection risk without causing extra side effects. It targets people considered higher risk for contamination of bile during surgery.
Leiden, South HollandAges 18–90 - NCT05846399RecruitingPhase 4
Test antibiotic prevention after a cat bite to the hand
This study tests whether taking a specific antibiotic right after a cat bite to the hand or forearm can help prevent an infection. You may be eligible if you arrive within 24 hours and don’t already have signs of infection.
Columbia, MissouriAges 18 years+ - NCT06387329RecruitingPhase 4
Antibiotic to prevent UTI after bladder Botox
This study tests whether taking a low-dose antibiotic (nitrofurantoin) before a Botox bladder injection can help prevent urinary tract infections. You may be able to join if you are getting Botox for overactive bladder or painful bladder syndrome and do not have frequent UTIs or other health issues that would make the antibiotic unsafe.
Bethesda, MarylandAges 18 years+ - NCT06488781RecruitingPhase 2
Antibiotics before labor induction for first-time moms with obesity
This study tests whether giving a single antibiotic (azithromycin) before labor induction can help prevent complications in first-time mothers who have obesity. It aims to make delivery safer for you and your baby.
Oklahoma City, OklahomaAges 15–45 - NCT04297592Enrolling by invitationPhase 4
Antibiotics to prevent infection after hip or knee replacement
This trial studies whether giving antibiotics before and/or after surgery can lower the chance of a serious joint infection after elective hip or knee replacement. It’s aimed at people at higher risk for infection.
Iowa City, IowaAges 18–99
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Common questions
- Are there clinical trials for antibiotic prophylaxis?
- Yes. Clin2 currently lists 32 recruiting antibiotic prophylaxis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a antibiotic prophylaxis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a antibiotic prophylaxis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.