Clinical trials
Antibiotic Prophylaxis clinical trials
Below are recruiting antibiotic prophylaxis clinical trials, each written for real people, not researchers. We’re tracking 34 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07557901Enrolling by invitation
Antibiotics to prevent infection after prostate biopsy
This study tests whether taking antibiotics before a prostate biopsy (a needle procedure to check for cancer) reduces infections. You would receive either standard care or a specific antibiotic plan, and researchers will track any infections that develop.
Banská BystricaAges Any age - NCT07067736Recruiting
Cefazolin Dose Before Shunt Surgery: Checking Brain Fluid Levels
This study measures how well the antibiotic cefazolin reaches the fluid around your brain and spine when given right before shunt surgery. It may help doctors choose the best dose to prevent infections.
StrasbourgAges 18 years+ - NCT07549542Enrolling by invitationPhase 4
Testing antibiotic delivery method for hip replacement surgery
This study compares a new way of delivering antibiotics directly into the bone during hip replacement surgery versus the standard IV method. The goal is to see if this approach prevents infection just as well while potentially improving outcomes.
Somerset, New JerseyAges 18 years+ - NCT05502380RecruitingPhase 3
Antibiotic prevention study for high-risk bone and spine surgeries
This Phase 3 study tests whether giving a broad set of preventive antibiotics before certain high-risk orthopedic surgeries lowers the chance of serious wound or bone infection. It mainly targets people who have contaminated wounds, tumor-related surgery, or known high-risk germs on the skin.
ZurichAges 18 years+ - NCT06709196RecruitingPhase 4
Targeted antibiotics to prevent infections after bladder removal
This trial tests if using a personalized antibiotic approach before surgery can reduce infections compared to the usual one-size-fits-all antibiotics. It focuses on people having their bladder removed (cystectomy) with a specific type of urinary diversion.
AalborgAges 18 years+ - NCT06810687Recruiting
Methenamine vs. antibiotics to prevent UTIs after sling surgery
This study compares a non-antibiotic medicine (methenamine) to antibiotics for preventing urinary tract infections after a common incontinence surgery (mid-urethral sling). It may help people avoid antibiotics and their side effects.
Morristown, New JerseyAges 18–100 - NCT06778083Recruiting
Antibiotic to prevent STIs and its effect on resistance
This study looks at taking doxycycline to prevent sexually transmitted infections (STIs) in men who have sex with men. It focuses on how this approach might affect the body's resistance to antibiotics.
LondonAges 18 years+ - NCT07053943Enrolling by invitation
Comparing single vs. multiple antibiotic doses for hip and knee replacement
This study compares two ways of giving antibiotics before hip or knee replacement surgery to see which one leads to fewer infections needing another surgery. It may help doctors choose the best antibiotic approach for patients having their first joint replacement.
Amsterdam, North HollandAges Any age - NCT07107477RecruitingPhase 3
Tailored therapy for preterm membrane rupture to prolong pregnancy
This trial tests a personalized treatment plan for people whose water breaks too early (before 34 weeks). The goal is to safely extend the pregnancy and improve health outcomes for both the parent and baby, while reducing the use of antibiotics.
BrnoAges 18 years+ - NCT05571722RecruitingPhase 4
Antibiotic prevention for surgical site infections
This trial tests whether using linezolid or vancomycin before surgery can better prevent infections at the surgical wound in people at higher risk. You might be considered because you either can’t take certain standard antibiotics (beta-lactams) and/or may carry MRSA bacteria.
MarseilleAges 18 years+ - NCT05519072RecruitingPhase 4
Antibiotics before bladder Botox injections
This study looks at whether taking antibiotic medicine before bladder Botox reduces infection risk or complications. It’s for adults having bladder Botox treatments and who can safely take antibiotics by mouth.
Morristown, New JerseyAges 18 years+ - NCT07246967Recruiting
Preventing infection after kidney stone surgery
This trial tests if using a special suction tube during surgery to remove kidney stones can lower the risk of infection. It is for people with small to medium-sized stones in the kidney or upper ureter.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07442357Recruiting
Antibiotics before heart valve replacement procedure trial
This trial is for patients getting a new aortic heart valve (TAVI). It tests whether giving antibiotics before the procedure helps prevent infections. If you are getting a TAVI in Denmark, you may be eligible.
AalborgAges 18 years+ - NCT04140578RecruitingPhase 4
Antibiotic prevention for certain liver disease patients
This trial tests whether taking preventive antibiotics can help people with certain liver conditions avoid infections after an endoscopy-related procedure. It may reduce infection risk, but it also requires that you have no signs of infection and haven’t recently taken antibiotics.
TaipeiAges 20–85 - NCT05784311RecruitingPhase 4
Longer vs shorter antibiotic prevention after pancreatoduodenectomy
This trial compares a standard length of preventive antibiotics versus a longer course after Whipple surgery to see if it lowers infection risk without causing extra side effects. It targets people considered higher risk for contamination of bile during surgery.
Leiden, South HollandAges 18–90 - NCT07561541RecruitingPhase 4
Extended Antibiotics for Diabetic Leg Fracture Surgery
This study tests whether taking antibiotics for a longer time helps prevent infections in people with poorly controlled diabetes who need surgery for a lower leg or foot fracture. Since diabetes makes infections more likely after surgery, extra antibiotics might reduce that risk.
Los Angeles, CaliforniaAges 18 years+ - NCT07558681Recruiting
Antibiotic dosing during liver and pancreas surgery
This study checks if the standard dose of an antibiotic (piperacillin/tazobactam) reaches effective levels in the blood during major liver or pancreas surgery. The goal is to improve infection prevention after surgery.
Vandœuvre-lès-Nancy, LorraineAges 18 years+ - NCT06387329RecruitingPhase 4
Antibiotic to prevent UTI after bladder Botox
This study tests whether taking a low-dose antibiotic (nitrofurantoin) before a Botox bladder injection can help prevent urinary tract infections. You may be able to join if you are getting Botox for overactive bladder or painful bladder syndrome and do not have frequent UTIs or other health issues that would make the antibiotic unsafe.
Bethesda, MarylandAges 18 years+ - NCT07342647Recruiting
Safer antibiotics for people with beta-lactam allergies in joint replacement surgery
This trial tests a better way to choose antibiotics during joint replacement surgery for patients who are allergic to beta-lactams (a common class of antibiotics). The goal is to prevent infections while avoiding allergic reactions.
StrasbourgAges 18 years+ - NCT07311395Recruiting
Gentamicin injection to prevent infection after planned C-section
This study tests whether a local injection of gentamicin, an antibiotic, into the incision area can help prevent infections after a planned C-section. It may offer extra protection beyond standard antibiotics.
NahariyaAges 18 years+ - NCT07183462RecruitingPhase 4
Antibiotic treatment for late preterm water breaking
This trial tests whether a combination of two antibiotics (azithromycin and ampicillin) can help pregnant people whose water has broken between 34 and 36 weeks of pregnancy. The goal is to see if this treatment improves outcomes for both the parent and baby without causing early labor or infection.
Ramat Gan, IsraelAges 18–50 - NCT07077122Recruiting
Comparing five gum disease treatments
This trial tests five different non-surgical gum treatments to see how they affect overall health. It may be a good fit for people with advanced gum disease who do not smoke heavily or take certain medications.
AthensAges Any age - NCT06953271RecruitingPhase 4
Methenamine after Botox for bladder control
This study tests whether taking a medication called methenamine hippurate (a pill for preventing UTIs) after Botox bladder injections can help reduce the risk of urinary tract infections. It may be a good option for women and non-binary people with overactive bladder who are already getting Botox treatment.
Providence, Rhode IslandAges 18 years+ - NCT06488781RecruitingPhase 2
Antibiotics before labor induction for first-time moms with obesity
This study tests whether giving a single antibiotic (azithromycin) before labor induction can help prevent complications in first-time mothers who have obesity. It aims to make delivery safer for you and your baby.
Oklahoma City, OklahomaAges 15–45
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Common questions
- Are there clinical trials for antibiotic prophylaxis?
- Yes. Clin2 currently lists 34 recruiting antibiotic prophylaxis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a antibiotic prophylaxis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a antibiotic prophylaxis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.