Shorter TB treatment for people 65 and older
Part of Infections, Lungs & breathing clinical trials.
This study tests a shorter-course treatment for tuberculosis (TB) in people 65 and older. It compares a new ultra-short regimen to the usual longer one, using the drugs bedaquiline, linezolid, and pyrazinamide, to see if a shorter treatment is just as effective and safer for older adults.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 65 years old or older
- You have active tuberculosis (TB) in your lungs, confirmed by a lab test that shows the TB germs are sensitive to the standard drug rifampicin
- You have not taken TB medication for active TB before starting this study
- You are willing to have an HIV test and to store blood/DNA samples for research
- You do not have HIV, uncontrolled diabetes, severe liver/kidney problems, or certain heart conditions
- You are not allergic or resistant to the study drugs (bedaquiline, linezolid, pyrazinamide)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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