Treatment
Linezolid clinical trials
We’re tracking 23 recruiting studies that include Linezolid, each written for real people, not researchers, below.
Recruiting studies
- NCT07477119RecruitingPhase 4
Personalized linezolid dosing for drug-resistant TB treatment
This trial tests whether adjusting the dose of linezolid based on regular blood tests can help people with multidrug-resistant tuberculosis (MDR-TB) tolerate the medication better while on the BPaL or BPaL-M regimen. It aims to reduce side effects and improve treatment success.
ConakryAges 15 years+ - NCT05369052RecruitingPhase 3
New antibiotic for moderate or severe diabetic foot infections
This Phase 3 trial tests a new medicine (contezolid acefosamil, and contezolid) to treat moderate or severe diabetic foot infections. It compares the new treatment to linezolid to see which works better and is safer for adults.
Corona, CaliforniaAges 18 years+ - NCT05571722RecruitingPhase 4
Antibiotic prevention for surgical site infections
This trial tests whether using linezolid or vancomycin before surgery can better prevent infections at the surgical wound in people at higher risk. You might be considered because you either can’t take certain standard antibiotics (beta-lactams) and/or may carry MRSA bacteria.
MarseilleAges 18 years+ - NCT05383742RecruitingPhase 2
Compare 6- vs 9-month treatment for tuberculous meningitis
This Phase 2 study tests whether a shorter, stronger 6-month set of medicines works as well as the usual 9-month regimen for tuberculous meningitis (TB infection in the covering of the brain/spinal cord). The goal is to improve outcomes while reducing treatment time and exposure.
Porto AlegreAges 15 years+ - NCT05398679RecruitingPhase 4
Oral antibiotics versus IV antibiotics after heart infection
This trial compares taking antibiotics by mouth versus receiving antibiotics through a vein (outpatient IV) for an infection of the heart valve. It’s designed to see whether the oral option can work as well and safely, especially after initial treatment and surgery if needed.
Alicante, AlicanteAges 18 years+ - NCT05534750RecruitingPhase 2
Early test of two antibiotics for new lung TB
This trial tests how quickly two antibiotics (tedizolid vs linezolid) can kill tuberculosis germs in the lungs after a first TB infection is suspected. It may help doctors learn which option works faster and safely in the early treatment phase.
ParisAges 18–75 - NCT06590428Recruiting
Tracking linezolid levels for rifampin-resistant TB treatment
This study checks if measuring the amount of linezolid medicine in your blood helps treat rifampin-resistant tuberculosis more safely and effectively. It is for people who have already started a treatment plan that includes linezolid.
East London, Eastern CapeAges 18 years+ - NCT06958835Recruiting
Linezolid plus standard care for staph bloodstream infections
This trial tests whether adding linezolid, an antibiotic that stops bacteria from making proteins, to usual care works better for treating Staphylococcus aureus bloodstream infections. You may be eligible if you have this infection and are hospitalized.
Aarau, Canton of AargauAges 18 years+ - NCT07672405RecruitingPhase 2
Sorfequiline-based treatment for new drug-sensitive TB
This study tests a new medicine called sorfequiline, given in a combination regimen, to treat adults with drug-sensitive TB. It aims to see if sorfequiline can work as well as or better than standard treatment and shorten the time to cure.
Port Elizabeth, BethelsdorpAges 18–65 - NCT06921213RecruitingPhase 2
Oral antibiotics for newborns exposed to syphilis
This study tests whether giving oral antibiotics at home is as safe and effective as the usual injections for newborns exposed to syphilis during pregnancy. It is for babies who appear healthy at birth.
JakartaAges birth–1 week - NCT06709196RecruitingPhase 4
Targeted antibiotics to prevent infections after bladder removal
This trial tests if using a personalized antibiotic approach before surgery can reduce infections compared to the usual one-size-fits-all antibiotics. It focuses on people having their bladder removed (cystectomy) with a specific type of urinary diversion.
AalborgAges 18 years+ - NCT07525427RecruitingPhase 2
New Tuberculosis Drug Study for Drug-Sensitive TB
This study tests a new tuberculosis drug called TBD09 combined with other TB medicines in people with newly diagnosed, drug-sensitive TB. The goal is to see if this combination works well and is safe.
Durban, BluffAges 18–65 - NCT04310930RecruitingPhase 2/Phase 3
Find the best treatment plan for a lung infection
This study looks for the best way to treat Mycobacterium abscessus (MABS), a difficult lung infection. You may join a treatment group, or first join an observation group and possibly move into treatment later if you meet the criteria.
Kogarah, New South WalesAges Any age - NCT06114628RecruitingPhase 2
Finding the best treatment for lung TB (PARADIGM4TB)
This study tests different ways to treat active lung TB that is not resistant to rifampicin. It aims to find the best treatment duration and combination to cure TB and prevent it from coming back.
ChisinauAges 18 years+ - NCT06192160RecruitingPhase 2
New TB drug combinations for drug-sensitive lung TB
This trial tests new combinations of TB medicines for people with active lung TB that is sensitive to standard drugs. It aims to find safer, shorter treatments that work just as well or better than current options.
GaboroneAges 18 years+ - NCT06336824RecruitingPhase 3
Switching from IV to oral antibiotics for staph bloodstream infection
This trial tests whether switching from IV antibiotics to oral antibiotics after 3–7 days is safe and effective for people with uncomplicated Staphylococcus aureus bloodstream infections. It may help you avoid a longer hospital stay and reduce IV-related complications.
Johor Bahru, JohorAges 18 years+ - NCT06441006RecruitingPhase 2/Phase 3
Personalized treatment for rifampicin-resistant TB
This trial tests a personalized treatment approach for people with rifampicin-resistant TB that is still sensitive to fluoroquinolones. It aims to find the best combination of medicines based on your specific TB profile.
UlaanbaatarAges 14 years+ - NCT06476210RecruitingPhase 4
New drug combo for drug-resistant tuberculosis
This trial tests a three-drug combination (bedaquiline, delamanid, and linezolid) to see if it's safe and works well for people with multi-drug resistant or rifampicin-resistant tuberculosis. It may offer a new treatment option if standard drugs aren't working.
Hefei, AnhuiAges 18 years+ - NCT06905522RecruitingPhase 3
Tuberculosis treatment trial for new patients
This trial tests a combination of drugs for people with active tuberculosis who have not been treated before. It aims to find a better way to treat TB, even if the bacteria are resistant to some drugs.
BeijingAges 18–65 - NCT07372781Enrolling by invitationPhase 2
Contezolid for mycobacterium abscessus lung infection
This study tests whether a new antibiotic, Contezolid, can quickly reduce the amount of Mycobacterium abscessus in your lungs. It may be a treatment option if you have had a positive sputum test in the past 6 months.
Beijing, Beijing MunicipalityAges 18–65 - NCT07228702Enrolling by invitationPhase 1
Bacteriophage therapy for one patient with lung infection
This is a special program for one patient with a lung infection from Mycobacterium abscessus. The trial uses a treatment with bacteriophages, which are viruses that attack specific bacteria.
Vancouver, British ColumbiaAges Any age - NCT06811025Enrolling by invitationPhase 1/Phase 2
Contezolid for treating tuberculous meningitis
This trial tests a new antibiotic called contezolid for people with tuberculous meningitis, an infection of the brain lining. The goal is to see if it works well and is safe.
Beijing, Beijing MunicipalityAges Any age - NCT06811012Enrolling by invitationPhase 1/Phase 2
Testing Contezolid for Bone and Joint Tuberculosis
This trial tests an antibiotic called contezolid for people with bone or joint tuberculosis. It aims to see if the drug can treat the infection effectively.
Beijing, Beijing MunicipalityAges Any age
What Linezolid is being studied for
Conditions with recruiting Linezolid studies.
Common questions
- Are there clinical trials studying Linezolid?
- Yes. Clin2 currently lists 23 recruiting studies that include Linezolid, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Linezolid trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Linezolid an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Linezolid or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.