Treatment
Isoniazid clinical trials
We’re tracking 18 recruiting studies that include Isoniazid, each written for real people, not researchers, below.
Recruiting studies
- NCT05383742RecruitingPhase 2
Compare 6- vs 9-month treatment for tuberculous meningitis
This Phase 2 study tests whether a shorter, stronger 6-month set of medicines works as well as the usual 9-month regimen for tuberculous meningitis (TB infection in the covering of the brain/spinal cord). The goal is to improve outcomes while reducing treatment time and exposure.
Porto AlegreAges 15 years+ - NCT07708779RecruitingPhase 1
Inhaled isoniazid for tuberculosis treatment
This trial tests inhaled isoniazid (medicine) given through a nebulizer to see how well it works and how safe it is. It's for people being treated for tuberculosis.
GroningenAges 18 years+ - NCT03474029RecruitingPhase 2/Phase 3
Daily rifapentine treatment test for latent tuberculosis infection
This trial studies whether taking rifapentine every day is safe and helps prevent active tuberculosis (TB) in people who have latent TB infection. It aims to find the best way to stop TB from becoming a serious illness later.
Denver, ColoradoAges Any age - NCT06022146RecruitingPhase 3
Short TB prevention for school contacts
This trial tests a very short (one-month) medicine course to prevent tuberculosis (TB) in students and school staff who have been exposed to someone with active TB. If you have latent TB infection (the germs are in your body but you're not sick), this treatment aims to stop it from turning into active TB disease.
Anshun, GuiyangAges 13 years+ - NCT07086820Recruiting
Window prophylaxis for preventing TB in children
This trial tests if a short course of medication can prevent tuberculosis (TB) in children and teenagers who have been in close contact with someone who has active TB. The goal is to see if this approach can stop them from developing the disease.
Calama, AntofagastaAges 5–17 - NCT06526221Enrolling by invitation
Urine test to check TB medication use
This study checks a simple urine test to see if people with TB are taking their medication (isoniazid) regularly. It aims to help doctors find out sooner if someone is missing doses, so they can offer extra support.
Chennai, Tamil NaduAges 18 years+ - NCT06568484RecruitingPhase 2/Phase 3
Preventing TB with bedaquiline in people exposed to TB
This study tests if bedaquiline can prevent tuberculosis (TB) in people who have been in close contact with someone with active TB, including people living with HIV. If you qualify, you would take the study medicine and be monitored to see if it prevents you from developing TB.
UlaanbaatarAges Any age - NCT05807399RecruitingPhase 2
Step2c trial for new, drug-susceptible lung TB
This Phase 2 study tests treatment for people with newly diagnosed, drug-susceptible pulmonary (lung) tuberculosis (TB). It aims to see whether the study treatment works well and is safe for curing TB.
LambarénéAges 18–65 - NCT06114628RecruitingPhase 2
Finding the best treatment for lung TB (PARADIGM4TB)
This study tests different ways to treat active lung TB that is not resistant to rifampicin. It aims to find the best treatment duration and combination to cure TB and prevent it from coming back.
ChisinauAges 18 years+ - NCT06192160RecruitingPhase 2
New TB drug combinations for drug-sensitive lung TB
This trial tests new combinations of TB medicines for people with active lung TB that is sensitive to standard drugs. It aims to find safer, shorter treatments that work just as well or better than current options.
GaboroneAges 18 years+ - NCT06199921RecruitingPhase 2
Atorvastatin plus TB treatment for new tuberculosis
This study tests whether adding the cholesterol drug atorvastatin to standard TB treatment helps people recover faster. It is for people with newly diagnosed, drug-sensitive tuberculosis who have not yet started treatment.
Zaria, Kaduna StateAges 12–65 - NCT06253715RecruitingPhase 3
Shorter TB treatment for children
This trial tests a shorter treatment for children with tuberculosis (TB) that is not drug-resistant. It aims to find out if a shorter regimen works as well as the standard longer one, making treatment easier for children and their families.
ChennaiAges birth–9 years - NCT06484530RecruitingPhase 4
Gene-guided NAC to prevent TB drug liver injury
This trial tests whether a medicine called N-acetylcysteine (NAC) can help prevent liver damage caused by standard TB drugs. If you have a higher risk of liver injury based on your genes, you may be given NAC along with your TB treatment.
Bangkok Noi, BangkokAges 18–80 - NCT06618573RecruitingPhase 2/Phase 3
Can isoniazid prevent TB in lupus patients?
This study tests if taking the TB prevention medicine isoniazid is safe for people with lupus (SLE). It may help protect you from getting tuberculosis while managing your lupus.
Bandung, West JavaAges 18–55 - NCT06748937RecruitingPhase 2
Testing alpibectir plus ethionamide for new TB
This study tests an experimental oral TB drug called alpibectir given together with ethionamide for people with newly diagnosed lung TB. The goal is to see how well the combination works and if it is safe.
Cape Town, Western CapeAges 18–65 - NCT06905522RecruitingPhase 3
Tuberculosis treatment trial for new patients
This trial tests a combination of drugs for people with active tuberculosis who have not been treated before. It aims to find a better way to treat TB, even if the bacteria are resistant to some drugs.
BeijingAges 18–65 - NCT07073638RecruitingPhase 2
Testing a new TB drug called RESP30TB in people with newly diagnosed TB
This trial tests a new drug, RESP30TB, to see if it is safe, tolerable, and can quickly kill TB bacteria in people with newly diagnosed, rifampicin-susceptible pulmonary TB. You may be eligible if you can produce sputum and meet other health criteria.
Cape Town, BellvilleAges 18–65 - NCT07303699RecruitingPhase 2
Atorvastatin with TB meds: a drug study for TB patients
This study tests if adding the cholesterol drug atorvastatin to standard TB treatment can help clear the infection faster. It looks at how the body processes the drugs and how well they work together.
Zaria, Kaduna StateAges 12 years+
What Isoniazid is being studied for
Conditions with recruiting Isoniazid studies.
Common questions
- Are there clinical trials studying Isoniazid?
- Yes. Clin2 currently lists 18 recruiting studies that include Isoniazid, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Isoniazid trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Isoniazid an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Isoniazid or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.