Delayed cord clamping and gentler surfactant for very premature babies
Part of Lungs & breathing clinical trials.
This study compares two ways of caring for very premature babies (born before 30 weeks): delaying clamping of the umbilical cord and giving a special medicine (surfactant) through a thin tube instead of using a breathing tube. The goal is to see if these gentler methods improve breathing and overall health compared with usual care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your baby is born between 23 weeks and 29 weeks plus 6 days of pregnancy.
- Your baby is born at Peking University Third Hospital.
- Your baby is breathing on their own right after birth and has a breathing problem called respiratory distress syndrome.
- Your baby has not had a breathing tube placed right after birth for other reasons.
- Your baby does not have major birth defects or severe complications like shock, air leaks, or early infection that affect breathing.
- Your baby is not already in another research study and the family plans to continue treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial gives a medication called surfactant early (when oxygen needs are slightly increased) to very premature babies with breathing trouble. It aims to see if this early treatment helps them breathe better without needing a breathing tube, potentially improving their outcomes.
This study tests a new medicine called APC-0101, a type of surfactant, for premature babies with breathing problems (respiratory distress syndrome). It may help their lungs work better and reduce the need for more breathing support.
This study tests a lung medication called pulmonary surfactant, given with different oxygen levels, to help very premature babies (born before 32 weeks) who have breathing difficulties. The goal is to see which oxygen level works best with non-invasive breathing support.
This trial looks at giving a “surfactant” medicine (a substance that helps keep baby lungs open) to newborns who have serious breathing problems soon after birth. It may help babies with neonatal respiratory distress or acute breathing distress, especially if they’re treated in the early time window.
This trial compares two types of surfactant (Calfactant and Poractant Alfa) given through a less invasive method to very premature babies with breathing problems. It aims to see if one works better at helping them breathe without needing a breathing tube.
This trial is testing a different way of giving breaths on a breathing machine to very premature babies. It aims to see which speed of lung inflation is gentler and helps babies' lungs work better. If your baby is on a special breathing machine that responds to their own breathing, this trial may help improve their breathing support.
Hear when a new NRDS trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.