Testing a new antibody treatment for anti-NMDAR brain disease
Part of Brain & nervous system, Immune system & allergy clinical trials.
This study tests a new medicine (ART5803) in people whose immune system attacks a brain receptor called NMDAR, causing encephalitis (brain swelling) or psychiatric symptoms. It aims to see if the medicine can reduce symptoms like confusion, memory problems, or psychosis.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a confirmed anti-NMDAR antibody in your spinal fluid or blood (a special test).
- You must be between 18 and 65 years old.
- Your symptoms must have lasted at least 4 months (for certain groups).
- You cannot have other serious brain conditions like multiple sclerosis.
- You must be willing to use birth control if you could become pregnant or get someone pregnant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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