Inhaled sedation safety for head trauma patients
Treatments studied
Part of Brain & nervous system, Injuries & trauma clinical trials.
This trial tests a new way to give sedation through a breathing mask (isoflurane gas) to people with severe head injuries. It aims to see if this method is safe and may help when IV sedatives alone are not enough.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are over 18 years old.
- You are in the intensive care unit for a severe head injury.
- You have been on at least two different IV sedatives for over 24 hours and still need sedation.
- You have not had a surgery where part of your skull was removed to relieve pressure.
- You and your family have no history of a rare reaction to anesthesia called malignant hyperthermia.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 4 trial tests whether giving ketamine during anesthesia is safe and helpful for adults with severe sudden brain injuries after surgery. It may improve how patients are sedated and cared for while they are on a breathing machine.
This trial compares inhaled isoflurane sedation to standard propofol sedation in deeply sedated patients on ventilators. It aims to see if inhaled sedation improves outcomes.
This trial provides access to an inhaled sedative (isoflurane) for ICU patients who are on a breathing tube and cannot be safely sedated with standard IV medicines. It aims to help patients who are agitated, need high doses of sedatives, or have side effects from current sedation.
This Phase 3 trial tests a sedation approach using inhaled (“volatile”) anesthesia gases for children who need a ventilator. It aims to improve comfort and brain-related outcomes while they stay on the breathing machine for at least a day.
This trial is comparing a new type of inhaled sedative (volatile sedation) to usual IV sedatives for people with ARDS who are on a ventilator in the ICU. It aims to see if it can help patients breathe better and recover more quickly.
This trial compares three common sedative medications used to control pressure inside the skull after a traumatic brain injury. The goal is to see which medication works best and is safest for recovery.
Hear when a new Traumatic Brain Injury trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.