Clinical trials
Heart Valve Diseases clinical trials
Below are recruiting heart valve diseases clinical trials, each written for real people, not researchers. We’re tracking 227 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04190602Recruiting
Registry study for NeoChord artificial mitral valve chord
This study keeps track of people who had NeoChord treatment to help understand how well it works in everyday care. You may be included if you had a certain type of mitral valve leakage (regurgitation) and the procedure happened after 2016.
BonnAges 18 years+ - NCT04954404Recruiting
Mitral valve procedure registry for Chinese patients in one center
This study is a registry (a way to track real-world outcomes) for people with mitral valve disease who receive a mitral valve procedure. It helps doctors understand how well these procedures work and what complications happen in patients like you.
Hangzhou, ZhejiangAges 18 years+ - NCT05397392Recruiting
Diagnosis and treatment plan for heart–kidney problems
This study looks at the best way to diagnose and treat different types of heart-and-kidney problems that happen together. It may help you (or your caregiver) get the right classification and treatment approach based on how your heart and kidneys are affected.
NanjingAges 18 years+ - NCT05595226Recruiting
Ultrasound-guided mitral valve repair to improve heart outcomes
This study looks at whether using a special heart ultrasound during surgery (called RT3D-TEE) can lead to better results for people having mitral valve repair. It’s mainly for certain types of chronic mitral valve leakage.
Beijing, Beijing MunicipalityAges 18–80 - NCT01653223Recruiting
Simvastatin to protect the heart during heart surgery
This trial looks at whether simvastatin (a cholesterol medicine) can help protect the heart during cardiac surgery. You might be invited if you’re having surgery for certain, non-complex heart conditions, but not if you have some specific related health problems.
Guangzhou, GuangdongAges 18 years+ - NCT04843072Recruiting
Comparing two new valve options for a failing replacement aortic valve
This trial compares two types of replacement heart valves (balloon-expandable and self-expanding) for people whose prior surgical aortic valve is no longer working. It looks at which valve type offers better outcomes when placed through a catheter in the leg.
Los Angeles, CaliforniaAges 18 years+ - NCT06223906Recruiting
Heart valve disease marker study
This study will collect information and blood samples from people with heart valve disease to find biological markers that may help doctors better understand and treat the condition in the future.
Beijing, Beijing MunicipalityAges 18–100 - NCT05114850Recruiting
Follow-up study for people treated with TricValve
This study looks back at patients who were successfully treated with TricValve bicaval valve devices and then follows up with their outcomes. You might join if you (or your legal guardian) agree to be included.
Sankt Pölten, Lower AustriaAges 18 years+ - NCT06383208Recruiting
Heart and kidney risk study for people with both diseases
This study looks at how well we can predict heart and kidney problems in people who have both coronary heart disease and chronic kidney disease. By analyzing certain markers, researchers hope to create a better risk assessment tool.
Beijing, Beijing MunicipalityAges 18–80 - NCT06235385Recruiting
European study on multiple and mixed valve disease
This study looks at people with multiple or mixed heart valve disease (moderate or severe) using echocardiography. It aims to learn more about how these conditions affect patients and help guide future care.
Paris, Île-de-France RegionAges 18 years+ - NCT07843004Recruiting
AI screening for undiagnosed heart valve disease
This study tests whether an artificial intelligence (AI) tool can help find people who have undiagnosed heart valve problems by analyzing their electrocardiogram (ECG) results. If you visit the emergency room and have an ECG, the AI might help identify if you need further heart tests.
New York, New YorkAges 40 years+ - NCT03674788Recruiting
Heart valve patients getting a catheter procedure
This is a registry that follows people who are having a catheter-based treatment for a heart valve problem. It helps doctors understand how these procedures work in real life and may improve future care.
LeuvenAges Any age - NCT06001073Recruiting
Heart and brain disease health prediction study
This study uses advanced health data to predict how heart and brain conditions may progress. It aims to help doctors provide better care for people with these diseases.
Xi'an, ShaanxiAges 3–80 - NCT06595992Recruiting
Observing moderate aortic valve disease over time
This study follows people with moderate aortic valve disease to learn how their condition changes. It does not test a new treatment but will help doctors better understand the disease.
Hangzhou, ZhejiangAges 18 years+ - NCT06387446Recruiting
Donated heart valve transplant for children and young adults
This study is testing a new way to replace a damaged heart valve using a donated valve (allograft) that may last longer and work better for children and young adults. It may be a good option if you need a new valve and have few other choices.
Boston, MassachusettsAges 4 weeks–50 years - NCT06025149Recruiting
Study of a New Biological Heart Valve 'UniLine'
This study tests a new biological heart valve called 'UniLine' for people who need to replace their mitral valve (the valve between the left heart chambers) or aortic valve (the main valve sending blood to the body) for the first time. If you qualify, you would have planned surgery (not an emergency) and need to be free of certain other serious health conditions.
Kemerovo, Kemerovo OblastAges 18–80 - NCT07715279RecruitingPhase 2
Vericiguat for slowing aortic valve calcium buildup
This trial tests if the drug vericiguat can slow down the buildup of calcium in the aortic valve, which causes it to narrow and stiffen. If you have mild-to-moderate aortic valve stenosis and meet the other criteria, this study may help protect your valve from getting worse.
Chengdu, SichuanAges 35–80 - NCT07700459Recruiting
Exercise prehabilitation for congenital heart surgery
This study tests whether a supervised exercise program before heart surgery can help adults with congenital heart disease recover better. You would join an exercise class 2–3 times a week for several weeks leading up to your operation.
LiverpoolAges 18 years+ - NCT06660524RecruitingPhase 4
Calcium-phosphorus therapy for heart valve disease
This trial tests a treatment to lower high calcium and phosphorus levels in your blood, which may slow down calcium buildup in heart valves. It may help people with kidney problems who have valve disease.
Beijing, Beijing MunicipalityAges 50 years+ - NCT07662317Recruiting
Heart surgery recovery registry study
This study collects information from people having heart surgery to help doctors learn more about recovery. If you are scheduled for surgery during the study period, you may be able to join.
Hangzhou, ZhejiangAges Any age - NCT07649330Recruiting
Myofascial Release for Heart Surgery Recovery
This study tests whether a hands-on soft-tissue massage technique can help reduce pain and stiffness in patients recovering from open-heart surgery. The goal is to see if it speeds up healing and improves quality of life after the procedure.
Kaohsiung CityAges 18 years+ - NCT05439863Recruiting
Valve procedure trial for severe aortic valve problems
This trial studies people with severe aortic valve disease who will receive a catheter-based valve replacement (TAVR). It aims to check how well this approach works for fixing a narrowed or leaky aortic valve, and to monitor outcomes afterward.
Nanjing, JiangsuAges 18 years+ - NCT07617844Recruiting
Advanced MRI imaging for heart disease diagnosis
This study uses advanced magnetic resonance imaging (MRI) scans to better understand and diagnose heart disease. If you have suspected or confirmed heart problems, this trial may help doctors get clearer pictures of your heart muscle and tissue to figure out what's causing your symptoms.
Hangzhou, ZhejiangAges 18 years+ - NCT07566624Recruiting
Registry study of Hydra heart valve replacement procedure
This study tracks patients who receive a Hydra artificial heart valve to replace a severely narrowed aortic valve. Researchers will follow your progress to understand how well the device works and its safety in real-world use.
Fuencarral-El PardoAges 18 years+
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Heart Valve Diseases trials by city
Studies with a site in or near these metro areas.
Heart Valve Diseases trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for heart valve diseases?
- Yes. Clin2 currently lists 227 recruiting heart valve diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart valve diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart valve diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.