Comparing two ablation approaches for persistent atrial fibrillation
Part of Heart & circulation clinical trials.
This trial tests whether adding extra ablation lines to the standard pulmonary vein isolation procedure is more effective for people with persistent atrial fibrillation that hasn't been helped by medications. The goal is to improve symptoms like palpitations, fatigue, and shortness of breath.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You have persistent atrial fibrillation that has lasted more than 90 days and is causing symptoms.
- You have tried at least one heart rhythm medication that didn't work or caused side effects.
- This would be your first ablation procedure for atrial fibrillation.
- You do not have certain other heart conditions, recent strokes, or serious kidney problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
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This trial tests a newer, possibly safer way to treat persistent atrial fibrillation using pulsed field ablation. It compares standard vein isolation alone to adding extra ablation spots to improve success.
This study tests a new way to perform ablation (a type of heart procedure) for people with persistent atrial fibrillation (AF) that hasn't responded well to medication. The goal is to see if a targeted approach to the left atrium's back wall works better than standard ablation.
This study tests whether adding a modification to a standard heart procedure (pulmonary vein isolation) works better for people with persistent atrial fibrillation (a type of irregular heartbeat that lasts a long time). It may help find the best way to treat this condition.
This trial tests whether blocking faulty heart signals from the pulmonary veins (with or without additional “substrate” modification) works better when electric cardioversion doesn’t stop persistent atrial fibrillation. It may help people who remain in atrial fibrillation after cardioversion by reducing symptoms and abnormal rhythm over time.
This study tests whether adding extra scar lines (linear ablation) to the standard pulmonary vein isolation (CPVI) is better than CPVI alone for people with long-standing persistent AF that has lasted 1 to 3 years. The goal is to see which approach reduces AF better.
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