Clin2
NCT07116824Possibly a fitNot yet recruiting

HB1801 combined therapy for HER2-positive breast cancer

HER2-positive Breast Cancer

Treatments studied

Part of Cancer clinical trials.

This study tests a new combination of targeted therapies (HB1801 with trastuzumab and pertuzumab) plus chemotherapy for people with HER2-positive breast cancer that has spread or come back. It aims to see if this treatment helps shrink tumors or slow their growth.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
80 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have breast cancer that is HER2-positive and has spread to other parts of the body or has returned locally and cannot be removed by surgery.
  • You have not had prior chemotherapy or HER2-targeted treatment for advanced or metastatic disease. (Previous hormonal therapy for up to 1 line is allowed.)
  • You have at least one measurable tumor that can be evaluated (but not only bone metastases as target).
  • You are 18 or older and your general health (ECOG score) is 0 or 1.
  • Your heart, liver, kidney, and blood counts are within acceptable ranges as per trial guidelines.
  • You are willing to use effective contraception if you are of childbearing potential or have a partner who is.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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