Checking if early skull surgery helps after a major stroke
Part of Brain & nervous system, Heart & circulation clinical trials.
This study looks at whether doing a surgery to remove part of the skull (decompressive hemicraniectomy) soon after removing a large blood clot from the brain helps people who have had a very severe stroke. It is for people who have had a stroke caused by a blockage in a major artery and have already had a procedure to open that artery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have had a very severe stroke in one side of the brain, affecting the middle cerebral artery or internal carotid artery.
- You must be between 18 and 75 years old.
- You must have had a procedure to remove the clot (mechanical thrombectomy) within 24 hours of when you were last seen well.
- You must be able to have the skull surgery within 6 hours after the clot removal procedure.
- You must not have any major bleeding in the brain or other serious brain diseases.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether emergency clot removal (endovascular therapy) can help people whose mild stroke gets worse within a week. It's for those who have a blockage in a large brain artery and enough healthy brain tissue to save.
This trial tests a surgical rescue treatment for people who have had a major stroke from a large artery blockage, but the standard clot removal procedure (thrombectomy) did not fully open the artery. The goal is to see if combining surgery with the earlier procedure can improve outcomes.
This study looks at immune and inflammation changes in the early period after a severe type of stroke that needs emergency brain decompression (hemicraniectomy). It compares people who have the procedure under certain conditions to other surgical patients to understand what’s driving recovery and complications.
This trial tests whether removing a certain type of brain bleed (intracerebral hemorrhage) very early, using a minimally invasive surgery approach, improves outcomes compared with standard treatment. It may help people whose bleed is large enough and who can have surgery within a strict time window.
This study looks at how MRI findings match what doctors see in brain tissue after treatment for a type of severe stroke. It may help researchers better understand which brain changes happen early and how decompressive surgery affects them.
This trial tests a minimally invasive procedure to remove blood clots from large brain arteries in people who have had a severe stroke. It may help reduce disability even when the stroke is extensive and was discovered up to 24 hours after symptoms began.
Hear when a new Cerebral Edema trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.