Metformin study for premature babies with lung disease
Treatments studied
Part of Genetic & congenital, Lungs & breathing, Women’s health & pregnancy clinical trials.
This study tests whether metformin, a medicine used for diabetes, can help premature babies with chronic lung disease (bronchopulmonary dysplasia, or BPD) breathe better. It may reduce the need for breathing machines.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your baby was born before 29 weeks of pregnancy.
- Your baby is either 8 to 22 weeks old with a BPD diagnosis at 36 weeks corrected, OR 7 to 30 days old and needed a breathing tube or strong breathing support at day 7.
- Your baby does not have persistent low blood sugar (hypoglycemia) or lactic acidosis.
- Your baby does not have feeding problems, kidney or liver issues, or an active infection.
- Your baby does not have a birth defect that prevents feeding, and you are not choosing only comfort care.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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