Predicting recovery with smell tests in coma
Part of Brain & nervous system clinical trials.
This study tests whether a simple smell test can help predict recovery of consciousness in patients who remain in a coma or minimally conscious state after a severe brain injury. If you or your loved one has been unresponsive for several days after sedation is stopped, this trial may provide useful information about prognosis.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are currently in a neuro-intensive care unit (specialized brain injury ICU).
- You are 18 years or older.
- You have been unconscious or minimally conscious for at least 72 hours after stopping sedation and starting to breathe on your own.
- Your legal representative has given permission, or an emergency waiver has been activated.
- You are covered by a health insurance or social security system.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial uses a combination of EEG (brain wave) and EMG (muscle activity) tests to see if they can predict recovery in people who have been unconscious or minimally conscious after a brain injury. Joining this study may help doctors better understand how to care for patients with these conditions.
This trial uses a portable brain scanner (fNIRS) to study brain activity in people with disorders of consciousness, like coma or minimally conscious states. It may help doctors better understand and track recovery in these patients. Healthy volunteers are also needed as a comparison group.
This study tries to predict how well people may recover after an acute severe brain injury that affects awareness (like coma). It uses information from the first few weeks after injury to guide expectations and future care.
This study looks at different ways to predict how people with severe disorders of consciousness might recover after a brain injury. It may help doctors better estimate prognosis and improve care planning.
This study checks how a brain responds to two kinds of sounds—neutral tones and emotional sounds—in people with a persistent disorder of consciousness after a serious event like stroke, head injury, or cardiac arrest. The goal is to see whether these brain “signal” tests can help doctors predict outcomes.
This study tests whether a daily smell training routine can help improve your sense of smell. It is open to adults with any kind of smell loss or problem, including those with conditions like COVID-19 or head injury, but not certain brain diseases.
Hear when a new Disorders of Consciousness Due to Severe Brain Injury trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.