Clin2
NCT07129681Possibly a fitNot yet recruiting

Sugar water injection vs. jaw washing for jaw clicking and pain

TMJ Disc Disorder

Treatments studied

Part of Bones, joints & muscles, Ear, nose & throat, Pain clinical trials.

This trial tests whether a simple injection of sugar water (dextrose 5%) into the jaw joint helps more than a standard jaw-washing procedure (arthrocentesis) for people whose jaw disc slips out of place (anterior disc displacement) and who haven't improved with physical therapy.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
42 people
Ages
18 years to 50 years
Study type
Interventional

Who can take part

  • You have been diagnosed with a jaw disc that slips out of place when you open and close your mouth, causing pain and clicking.
  • You have limited mouth opening and painful clicking in your jaw joint.
  • You tried physical therapy for at least 3 months, but it did not help.
  • You are between 18 and 50 years old.
  • You can attend follow-up visits to check how you are doing.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06859034Not yet recruiting· Phase 2/Phase 3
Sugar injections for jaw joint pain: comparing two doses

This clinical trial tests whether injecting a sugar solution (dextrose) into the jaw joint can reduce pain and improve function. It compares a 25% concentration to a 10% concentration in people whose jaw disc moves out of place but goes back in (with a click). You will not know which dose you receive.

NCT07614932Not yet recruiting
Jaw Surgery With and Without Hyaluronic Acid Injection

This trial tests a minimally invasive jaw surgery (arthroscopy) to treat a specific jaw disc problem that hasn't improved with conservative treatments like physical therapy or mouth guards. Half of patients will also receive a hyaluronic acid injection, which may reduce inflammation and improve jaw function.

Cairo
NCT07107399Not yet recruiting· Phase 2/Phase 3
Fat or platelet injection for jaw disc pain

This study compares a new treatment using your own fat cells (Lipogems) with a platelet-rich plasma (PRP) injection to see which better helps jaw pain and clicking caused by a slipped disc. Both treatments are injected into the jaw joint and aim to improve how wide you can open your mouth.

NCT06839430Not yet recruiting
Injections for painful jaw clicking

This trial compares two types of injections (hypertonic saline and dextrose) to see which one works better for painful jaw clicking and related discomfort. It may help if other treatments (like a mouthguard or physical therapy) haven't worked.

NCT07115797Not yet recruiting
Comparing treatments for jaw joint disc displacement

This trial compares two treatments for a jaw joint problem where the disc is out of place. One treatment is a procedure called arthroscopic surgery (ARS), the other is ARS with a joint washout and injection of platelet-rich plasma (PRP) to help healing. This study aims to see which approach works better for pain and clicking.

NCT07598253Not yet recruiting
Jaw Joint Treatment with Injectable Medication

This trial tests injecting medication directly into the temporomandibular joint (TMJ)—the hinge joint in front of your ear where your jaw moves—to treat jaw pain, clicking, or difficulty opening your mouth. The goal is to reduce these symptoms and improve how well your jaw works.

Cairo, Cairo Governorate

Hear when a new TMJ Disc Disorder trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.