Heart monitor and nerve treatment for recurrent fainting
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests a device called an implantable loop recorder (a small monitor placed under the skin) along with a procedure called cardioneuroablation, which targets nerves that may cause fainting. It is designed for people with frequent, severe fainting due to reflex syncope.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 18 and 60 years old.
- Have a confirmed diagnosis of reflex syncope (a type of fainting caused by a reflex that slows the heart or drops blood pressure).
- Have fainted at least twice in the last year, or three times in the last two years, despite trying lifestyle changes.
- Have a heart monitor or tilt-table test that showed your heart pauses for more than 3 seconds when you faint.
- Not have other heart problems, low blood pressure when standing, or another cause for your fainting.
- Not be pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies treatments for a type of fainting caused by the body’s reflex slowing the heart. It compares a permanent pacemaker with a procedure called cardiac nerve ablation to see which helps prevent fainting and improves quality of life.
This study tests a new way to detect and warn about fainting in people with certain types of syncope (temporary loss of consciousness). It may help those who have already had a specific fainting evaluation called an ARS assessment.
This trial tests a procedure called cardioneuroablation to treat severe fainting (reflex syncope) that hasn't been helped by other treatments. The goal is to see if it reduces fainting without causing dangerous heart rhythm problems.
This trial studies a procedure that targets a specific heart nerve area on the right side to reduce neurally mediated fainting (syncope). You may be a candidate if your fainting is linked to heart rhythm/nerve reflexes and you meet several heart-function and heart-rhythm test criteria.
This study tests a procedure called cardioneuroablation, which uses targeted heat (radiofrequency) to calm overactive nerves that cause your heart to beat too slowly and make you faint. The goal is to stop severe fainting spells in people with reflex syncope who haven't gotten better with other treatments.
This study looks at people who have had repeated fainting spells and still don’t know the cause. It tests whether different types of heart monitoring (like tilt testing or an ECG/heart tracing) can better explain what’s triggering syncope and guide prevention.
Hear when a new Reflex Syncope trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.