Cooling artery treatment with magnesium for stroke clot removal
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests adding a cooled magnesium solution directly into the brain artery during standard clot removal to see if it helps limit brain damage and improve recovery. The magnesium and cooling aim to protect brain tissue while the clot is being taken out.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old
- You have had a stroke caused by a clot in a large artery in the front part of the brain
- Your stroke symptoms started within the last 24 hours and you are able to have a mechanical clot removal procedure
- Your stroke is moderately severe to severe (NIHSS score of 6 or higher)
- You were independent before the stroke (able to do daily activities without help)
- You do not have major bleeding risk, active infection, severe heart/lung/kidney/liver problems, or are pregnant
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether giving a cold magnesium solution directly to the brain during clot removal improves recovery after a stroke. It aims to protect brain cells while the blocked vessel is reopened.
This trial tests whether giving magnesium directly into the artery during mechanical thrombectomy (a procedure to remove a blood clot from the brain) improves recovery after a severe ischemic stroke. Magnesium may help protect brain cells from further damage after the clot is removed.
This trial tests whether giving a clot-dissolving medication directly into the brain's blood vessels during a standard procedure (mechanical thrombectomy) can improve outcomes for people with a stroke caused by a blockage in a medium-sized artery. It may be an option for patients who arrive at the hospital within 24 hours of symptom onset and have enough salvageable brain tissue.
This trial tests if removing a large blood clot from the brain up to 3 days after a stroke improves recovery compared to standard medical care alone. It is for patients who have a severe stroke and are otherwise healthy enough for the procedure.
This trial tests whether cooling the head during a clot-removal procedure (thrombectomy) can improve recovery after a stroke. It might help reduce brain damage and improve long-term outcomes.
This trial tests whether emergency clot removal (endovascular therapy) can help people whose mild stroke gets worse within a week. It's for those who have a blockage in a large brain artery and enough healthy brain tissue to save.
Hear when a new Acute Ischemic Stroke trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.