Magnesium during clot removal for severe stroke
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests whether giving magnesium directly into the artery during mechanical thrombectomy (a procedure to remove a blood clot from the brain) improves recovery after a severe ischemic stroke. Magnesium may help protect brain cells from further damage after the clot is removed.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had a stroke caused by a blockage in a major artery in your brain (the carotid or middle cerebral artery).
- You have moderate to severe symptoms from the stroke, but not the very worst cases.
- You were independent before the stroke, meaning you could do daily activities without help (allowed to have minor issues).
- Your doctor plans to do a mechanical thrombectomy (a procedure to remove the clot) as part of your routine care.
- The clot removal procedure must be successful (blood flow restored to at least 50% or better).
- You can receive magnesium safely, so you cannot have severe kidney or liver problems, a very slow heartbeat without a pacemaker, a bleeding disorder, or be on certain medications like blood thinners or sedatives.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether giving a cold magnesium solution directly to the brain during clot removal improves recovery after a stroke. It aims to protect brain cells while the blocked vessel is reopened.
This trial tests adding a cooled magnesium solution directly into the brain artery during standard clot removal to see if it helps limit brain damage and improve recovery. The magnesium and cooling aim to protect brain tissue while the clot is being taken out.
This trial tests whether giving a clot-dissolving medication directly into the brain's blood vessels during a standard procedure (mechanical thrombectomy) can improve outcomes for people with a stroke caused by a blockage in a medium-sized artery. It may be an option for patients who arrive at the hospital within 24 hours of symptom onset and have enough salvageable brain tissue.
This trial tests if removing a large blood clot from the brain up to 3 days after a stroke improves recovery compared to standard medical care alone. It is for patients who have a severe stroke and are otherwise healthy enough for the procedure.
This trial tests if giving a clot-busting drug (tenecteplase) directly into the brain artery after a successful clot-removal procedure can improve outcomes for people with a major stroke. It is for patients who had a large vessel blockage and received endovascular thrombectomy within 24 hours of symptoms starting.
This Phase 3 trial studies whether removing a clot using a catheter (endovascular thrombectomy) works better for certain types of acute ischemic stroke. It focuses on people with a blocked neck artery plus a blockage in the brain, and who can’t get or didn’t respond to IV clot-busting medicine.
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