Testing Calderasib for advanced solid tumors with KRAS G12C mutation
Treatments studied
Part of Cancer clinical trials.
This trial tests a new drug, Calderasib (MK-1084), for people with advanced solid tumors that have a specific KRAS G12C mutation and aren't getting better with standard treatments. The goal is to see if the drug can help shrink or control the cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have an advanced solid tumor (not colorectal cancer) that is either too large to remove or has spread to other parts of the body.
- Your cancer has gotten worse after trying standard treatments.
- Your tumor has a specific gene change called KRAS G12C.
- You do not have serious, uncontrolled heart problems or a recent stroke.
- You have no other growing cancers or active brain tumors that need treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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