Sivelestat for septic shock with blood clotting problems
Treatments studied
Part of Blood & lymphatic, Heart & circulation, Infections clinical trials.
This trial tests if the drug Sivelestat can help people in the intensive care unit who have septic shock and a specific type of blood clotting problem. It aims to improve survival and recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Are between 18 and 85 years old
- Have septic shock (a severe infection causing very low blood pressure that needs medicine to raise it)
- Have a blood clotting problem related to sepsis (measured by a score of 4 or higher on the SIC scale)
- Can start the study drug within 12 hours of the clotting problem being found
- Weigh 100 kg (about 220 pounds) or less
- Do not have severe liver disease (Child-Pugh C)
- Are not pregnant or breastfeeding
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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