Clin2
NCT07241390Possibly a fitRecruiting

Study of orforglipron for heart and kidney health.

Atherosclerosis Cardiovascular DiseaseChronic Kidney Disease

Treatments studied

Part of Brain & nervous system, Heart & circulation, Kidney & urinary, Women’s health & pregnancy clinical trials.

This trial tests if orforglipron can reduce the risk of heart attack, stroke, or kidney failure in people with heart disease or chronic kidney disease.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
7,140 people
Ages
50 years and older
Study type
Interventional

Who can take part

  • You have been diagnosed with heart disease (like a previous heart attack or blocked arteries) or chronic kidney disease.
  • You do not have type 1 diabetes.
  • You have not had a major heart event (like a heart attack or stroke) in the last 2 months.
  • Your heart failure is not severe (Class IV is the most severe type).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07753993Recruiting· Phase 3
Study of elecoglipron for chronic kidney disease

This trial tests an investigational medicine called elecoglipron for people with chronic kidney disease. It aims to see if it can improve kidney health compared to a placebo (inactive pill) and may be an option for those already on standard blood pressure and kidney protective medications.

Huntsville, Alabama
NCT07835828Recruiting
Optimised heart and kidney protection for chronic kidney disease and heart disease

This study tests a new approach to protect the heart and kidneys in people with both chronic kidney disease and heart or blood vessel problems. By optimising treatment, researchers hope to reduce the risk of further kidney or heart damage.

Svendborg
NCT07794579Recruiting· Phase 3
Study of orforglipron for people with overweight at risk of health problems

This trial tests a new medicine, orforglipron, to help people with overweight who are at risk of developing weight-related health issues. It aims to see if the medicine can help with weight management and reduce risks before more serious conditions develop.

Anniston, Alabama
NCT07223593Recruiting· Phase 3
Orforglipron for peripheral artery disease with leg pain

This trial tests a new oral medication called orforglipron to see if it can improve walking distance in people with peripheral artery disease (PAD) who have leg pain when walking. It may be a good option if you have PAD and your walking is limited by leg cramping, not other health issues.

Birmingham, Alabama
NCT07790861Not yet recruiting· Phase 3
Weight loss study for Chinese adults with excess weight

This study tests an investigational medication, orforglipron, taken as a pill to help people with excess weight lose weight. It may be an option for people who have not been able to lose weight with diet alone and who also have weight-related health problems.

Chengdu
NCT07739537Not yet recruiting· Phase 4
Study of gut response to a diabetes pill in adults

This study tests how your body responds to a new diabetes pill, orforglipron, by looking at hormones and blood sugar. The results may help doctors choose the best treatment for people with type 2 diabetes.

Hear when a new Atherosclerosis Cardiovascular Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.