Medications to reduce disability after a small stroke
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This study tests two medications, isosorbide mononitrate and butylphthalide, to see if taking them early after a small type of stroke (called lacunar) can reduce the chances of long-term disability. You would receive one of these medications or a placebo, and the study will follow your recovery over time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 30 years old or older.
- You had a recent 'lacunar' stroke (a small stroke in the deep part of the brain) within the last 7 days.
- You had a CT or MRI showing a small recent stroke, or if not, your symptoms lasted more than 24 hours.
- Your thinking and memory are within a certain range, based on your education level (tested with a short questionnaire).
- You were able to do your everyday activities independently before this stroke (no serious disability).
- You do not have severe heart, bleeding, liver, or kidney problems, and are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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