UDCA to prevent confusion after TIPS procedure
Part of Brain & nervous system, Digestive system, Hormones & metabolism clinical trials.
This study tests whether a medicine called UDCA (ursodeoxycholic acid) can prevent confusion and other brain-related problems after a TIPS procedure. TIPS is a procedure that helps blood flow through the liver. The study compares UDCA to a placebo (a dummy pill) to see if UDCA helps reduce these complications.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You have liver cirrhosis (a type of liver disease) confirmed by your doctor.
- You are scheduled to have a TIPS procedure for fluid in the belly (ascites) or bleeding from veins in your food pipe that comes back.
- You need to be able to start taking the study medicine within 3 days (72 hours) before the TIPS procedure.
- You have not taken UDCA or rifaximin in the past 3 months, and you are not taking them now.
- You have not had severe confusion (hepatic encephalopathy) before without a clear cause, and you do not have other brain diseases like Parkinson's or Alzheimer's.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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