Comparing pain relief after shoulder replacement
Treatments studied
Part of Brain & nervous system clinical trials.
This study compares two ways to manage pain after shoulder replacement surgery: a long-acting numbing medicine (ZYNRELEF) versus a temporary nerve block catheter. It aims to see which provides better pain control and recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older
- You are having your first total shoulder replacement (not a revision or for a fracture)
- You do not have kidney problems (CrCl less than 50)
- Your BMI is 40 or less
- You have not taken opioid painkillers regularly in the last 6 months
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests whether adding an extra numbing shot (pectoserratus block) to the standard shoulder block reduces pain after total shoulder replacement. It may help you recover more comfortably and use fewer pain medicines.
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This study compares two different strengths of local anesthetic used in a nerve block for shoulder replacement surgery. The goal is to see if one strength helps reduce pain that can come back as the block wears off.
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