Clin2
NCT07770165Possibly a fitNot yet recruiting

Continuous nerve block after shoulder replacement to reduce rebound pain

Total Shoulder ArthroplastyReverse Total Shoulder ArthroplastyInterscalene AnalgesiaInterscalene BlocksInterscalene Nerve BlockOrthopedic Surgery PatientsLocoregional AnaesthesiaRebound Pain

Part of Bones, joints & muscles, Pain clinical trials.

This study tests whether giving a continuous nerve block (an ongoing numbing medicine near the shoulder) can reduce 'rebound pain'—the sharp increase in pain that often happens after the block wears off—following shoulder replacement surgery done as an outpatient. If you qualify, you might have better pain control and a smoother recovery at home.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
154 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older.
  • You must be scheduled for a first-time (not revision) outpatient total shoulder replacement.
  • You are in generally good health (classified as ASA I–III).
  • You do not have chronic pain or take daily opioid pain medication.
  • You are not at high risk for complications from a nerve block (e.g., no bleeding issues, no allergy to local anesthetics, no infection near the injection site).
  • You must not have severe respiratory disease or a paralyzed diaphragm on the opposite side.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07146685Recruiting· Phase 4
Testing different strengths of numbing medicine for shoulder replacement

This study compares two different strengths of local anesthetic used in a nerve block for shoulder replacement surgery. The goal is to see if one strength helps reduce pain that can come back as the block wears off.

Charlottesville, Virginia
NCT07280195Enrolling by invitation· Phase 4
Comparing pain relief after shoulder replacement

This study compares two ways to manage pain after shoulder replacement surgery: a long-acting numbing medicine (ZYNRELEF) versus a temporary nerve block catheter. It aims to see which provides better pain control and recovery.

St Louis, Missouri
NCT05868330Recruiting· Phase 4
Compare two nerve-block methods for shoulder replacement

This trial compares two different ways of giving numbing medicine around the shoulder nerve before reverse shoulder replacement surgery. It may help find which method works better for pain control and comfort after surgery.

Iowa City, Iowa
NCT07831096Recruiting
Nerve block comparison for shoulder surgery pain relief

This study compares two types of nerve blocks to see which one provides better pain relief after outpatient shoulder surgery. Participants will receive one of the two blocks, and the study will track their pain and recovery.

Varese, Italy
NCT06754657Recruiting· Phase 4
Comparing pain blocks for rotator cuff surgery recovery

This trial tests two ways of numbing the shoulder during rotator cuff surgery to see which leads to better recovery after outpatient surgery. It compares a single injection with a continuous pump that delivers numbing medicine for a longer time.

Santiago
NCT07668648Recruiting
Two nerve blocks for shoulder surgery pain relief

This study compares two types of nerve blocks to reduce pain after shoulder surgery. One block is placed near the neck (interscalene) and the other is placed further away (serratus posterior superior intercostal plane block). The goal is to see which works better and has fewer side effects.

Bursa, Nilüfer

Hear when a new Total Shoulder Arthroplasty trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.