Clin2
NCT07285213Likely a fitRecruiting

Preventing C. diff return with an antibody

Clostridioides Difficile Infection

Part of Infections clinical trials.

This study tests a new antibody (AZD5148) to prevent C. diff infection from coming back. If you have a current C. diff infection and are being treated with antibiotics, you may be able to join.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
230 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older.
  • You must have or be recovering from a C. diff infection with diarrhea (at least 3 loose stools in 24 hours for 2 days) and a positive stool test.
  • You must be starting or already taking an antibiotic for this C. diff infection, with a planned treatment of 10 to 28 days.
  • You must weigh at least 77 pounds (35 kg).
  • You should not have had a fecal transplant or be planning one within the next 6 months, and you should not have had the C. diff antibody bezlotoxumab in the last 6 months.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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