Clin2
NCT07613645Possibly a fitRecruiting

Lifestyle changes to prevent recurring C. difficile infection

Clostridioides Difficile Infection

Part of Infections clinical trials.

This study tests whether specific lifestyle changes during treatment for C. difficile infection (a serious gut bacteria infection) can help prevent it from coming back. You'll receive standard antibiotic treatment and follow a controlled diet while researchers track your recovery.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
20 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • Have a first or non-recurring C. difficile infection confirmed by lab test
  • Be starting or currently receiving standard antibiotic treatment (fidaxomicin or vancomycin)
  • Never had advanced treatments for C. difficile like fecal transplant or prolonged antibiotics
  • Be able to follow a prepared study diet and stop taking probiotic supplements
  • Not be hospitalized or in a nursing facility when your antibiotic treatment ends
  • Be able to provide stool samples for testing throughout the study

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05266807Recruiting· Phase 3
Capsule fecal transplant to prevent C. difficile coming back

This study tests whether taking a capsule form of fecal microbiota transplant (FMT) can help adults with their first C. difficile infection—or a first relapse—get better and reduce repeat episodes. Participants also take specific antibiotics for C. difficile as part of the study process.

Basel, Basel
NCT07120490Not yet recruiting
Comparing treatments for C. diff infection to stop it from returning

This trial compares three treatments for a severe diarrhea infection called C. diff: a fecal transplant (putting healthy donor stool into your gut), a newer antibiotic called fidaxomicin, and an older antibiotic called vancomycin. The goal is to see which works best and prevents the infection from coming back.

NCT06306014Recruiting· Phase 1/Phase 2
Study of a new therapy to prevent C. diff recurrence

This study tests a new live bacteria product (EXL01) given with vancomycin to prevent C. diff from coming back. It is for people who have already had C. diff two or more times and are at high risk of another infection.

Annecy
NCT06884748Not yet recruiting· Early Phase 1
Adding bile acid treatment to prevent C. diff from returning

This study tests whether adding a common bile acid (ursodeoxycholic acid) to your regular C. diff treatment can help stop the infection from coming back. The goal is to see if this extra medicine reduces the chance of recurrence.

Milwaukee, Wisconsin
NCT07285213Recruiting· Phase 2
Preventing C. diff return with an antibody

This study tests a new antibody (AZD5148) to prevent C. diff infection from coming back. If you have a current C. diff infection and are being treated with antibiotics, you may be able to join.

Phoenix, Arizona
NCT06237452Recruiting· Phase 3
VE303 to prevent repeat C. diff infections

This trial tests a new medicine called VE303, a live bacterial therapy, to prevent C. diff infections from coming back. It is for people who have had C. diff at least once in the last 6 months, or who are at high risk for a repeat infection due to age or other health problems.

Huntsville, Alabama

Hear when a new Clostridioides Difficile Infection trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.