Liquid S-PRF for gum disease treatment
Treatments studied
Part of Mouth & dental clinical trials.
This study tests whether a special liquid made from your own blood (called liquid S-PRF) can improve gum health during deep cleaning for people with advanced gum disease. It lasts 3 months and may help reduce inflammation and promote healing without surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have at least 20 natural teeth.
- You must have gum disease (periodontitis) that a dentist has graded as stage 2, 3, or 4.
- Deep gum pockets of 5 millimeters or more must be on both sides of your mouth.
- You cannot currently smoke or vape, nor have you ever smoked or vaped.
- You must not have diabetes, a bleeding disorder, autoimmune disease, or be on blood thinners or immune-suppressing drugs.
- You cannot have had gum treatment, surgery, or taken certain medications in the past 3–6 months, and you cannot be pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether a special blood-derived gel (called Alb-PRF) can improve the results of standard deep cleaning for gum disease. If you qualify, half your mouth will get the standard treatment and the other half will get the standard treatment plus this gel, to see which works better.
This trial tests if adding platelet-rich fibrin (a natural healing concentrate from your blood) to standard deep cleaning improves treatment for advanced gum disease. It may help patients with widespread gum disease who have not had treatment in the last year.
This trial tests whether adding I-PRF (a concentrate from your own blood), povidone-iodine, or laser treatment to standard deep-cleaning helps smokers and non-smokers with gum disease. You may qualify if you have moderate to severe gum disease with at least one bleeding pocket in each area of your mouth.
This trial tests a treatment for deep gum disease pockets using a combination of your own blood components (injectable platelet-rich fibrin) and a bone graft material. It aims to help regenerate bone lost to periodontitis.
This study tests whether adding a special injection made from your own blood (platelet-rich fibrin) to standard deep-cleaning gum treatment helps improve gum health more than the cleaning alone. It may help reduce gum pocket depths and improve healing.
This study tests whether adding a special gel made from your own blood (albumin-PRF) to standard gum surgery helps your gums and bone heal better. It is for people with severe gum disease (periodontitis) who have already had a basic deep cleaning and still have deep pockets between their teeth.
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